metformin has been researched along with Venous Thromboembolism in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Venous Thromboembolism: Obstruction of a vein or VEINS (embolism) by a blood clot (THROMBUS) in the blood stream.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin is hypothesized to protect against the risk of venous thromboembolism (VTE); however, there is a paucity of data supporting this hypothesis." | 8.12 | Association of Metformin Use With Risk of Venous Thromboembolism in Adults With Type 2 Diabetes: A General-Population-Based Cohort Study. ( Lei, G; Li, C; Li, X; Sha, T; Wei, J; Wu, J; Yang, Z; Zeng, C; Zhang, Y, 2022) |
| " Indirect evidence from populations without PCOS demonstrated no increased risk of lactic acidosis with metformin, only case reports of liver toxicity with flutamide (no comparative evidence), and increased relative risk difference of venous thromboembolism with oral contraceptive pills but very low absolute risk." | 4.89 | Adverse effects of the common treatments for polycystic ovary syndrome: a systematic review and meta-analysis. ( Domecq, JP; Ehrmann, D; Erwin, PJ; Montori, VM; Mullan, RJ; Murad, MH; Prutsky, G; Sundaresh, V; Wang, AT; Welt, C, 2013) |
| "Metformin is hypothesized to protect against the risk of venous thromboembolism (VTE); however, there is a paucity of data supporting this hypothesis." | 4.12 | Association of Metformin Use With Risk of Venous Thromboembolism in Adults With Type 2 Diabetes: A General-Population-Based Cohort Study. ( Lei, G; Li, C; Li, X; Sha, T; Wei, J; Wu, J; Yang, Z; Zeng, C; Zhang, Y, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sha, T | 1 |
| Zhang, Y | 1 |
| Li, C | 1 |
| Lei, G | 1 |
| Wu, J | 1 |
| Li, X | 1 |
| Yang, Z | 1 |
| Zeng, C | 1 |
| Wei, J | 1 |
| Domecq, JP | 1 |
| Prutsky, G | 1 |
| Mullan, RJ | 1 |
| Sundaresh, V | 1 |
| Wang, AT | 1 |
| Erwin, PJ | 1 |
| Welt, C | 1 |
| Ehrmann, D | 1 |
| Montori, VM | 1 |
| Murad, MH | 1 |
1 review available for metformin and Venous Thromboembolism
| Article | Year |
|---|---|
Adverse effects of the common treatments for polycystic ovary syndrome: a systematic review and meta-analysis.
Topics: Androgen Antagonists; Contraceptives, Oral; Evidence-Based Medicine; Female; Flutamide; Humans; Hypo | 2013 |
1 other study available for metformin and Venous Thromboembolism
| Article | Year |
|---|---|
Association of Metformin Use With Risk of Venous Thromboembolism in Adults With Type 2 Diabetes: A General-Population-Based Cohort Study.
Topics: Adult; Cohort Studies; Diabetes Mellitus, Type 2; Humans; Incidence; Metformin; Pulmonary Embolism; | 2022 |