metformin has been researched along with Thyroid Diseases in 9 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Thyroid Diseases: Pathological processes involving the THYROID GLAND.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The acute and long-term effects of metformin on thyroid axis hormones were assessed in diabetic patients with primary hypothyroidism who were either untreated or treated with levothyroxine (L-T4), as well as in diabetic patients with normal thyroid function." | 5.14 | TSH-lowering effect of metformin in type 2 diabetic patients: differences between euthyroid, untreated hypothyroid, and euthyroid on L-T4 therapy patients. ( Agabiti-Rosei, E; Agosti, B; Cappelli, C; Castellano, M; Chiovato, L; Cimino, A; De Martino, E; Gandossi, E; Pirola, I; Rotondi, M; Valentini, U, 2009) |
| "The increased risk of type 2 diabetes and cardiovascular disease in PCOS is closely associated with BMI." | 2.55 | Medical comorbidity in polycystic ovary syndrome with special focus on cardiometabolic, autoimmune, hepatic and cancer diseases: an updated review. ( Andersen, M; Glintborg, D, 2017) |
| "The paper gives an update on type 2 diabetes mellitus concurrent with thyroid dysfunction and on the development of vascular events, atherogenesis and evaluates the impact of therapy on the course of both diseases." | 2.50 | [Thyroid dysfunction in patients with type 2 diabetes mellitus]. ( Suslina, AA; Tereshchenko, IV, 2014) |
| "Metabolic syndrome has been associated with nodular goiter." | 1.42 | Association between worse metabolic control and increased thyroid volume and nodular disease in elderly adults with metabolic syndrome. ( Barreto, A; Blanc, E; Brenta, G; Brodschi, D; Cejas, C; Faingold, C; Fossati, P; Musso, C; Nepote, A; Ponce, C; Salgado, P; Schnitman, M, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Grigoriadis, G | 1 |
| Koufakis, T | 1 |
| Kotsa, K | 1 |
| Glintborg, D | 1 |
| Andersen, M | 1 |
| Kalra, S | 1 |
| Khandelwal, D | 1 |
| Ke, RW | 1 |
| Tereshchenko, IV | 1 |
| Suslina, AA | 1 |
| Blanc, E | 1 |
| Ponce, C | 1 |
| Brodschi, D | 1 |
| Nepote, A | 1 |
| Barreto, A | 1 |
| Schnitman, M | 1 |
| Fossati, P | 1 |
| Salgado, P | 1 |
| Cejas, C | 1 |
| Faingold, C | 1 |
| Musso, C | 1 |
| Brenta, G | 1 |
| Meng, X | 1 |
| Xu, S | 1 |
| Chen, G | 1 |
| Derwahl, M | 1 |
| Liu, C | 1 |
| Cappelli, C | 1 |
| Rotondi, M | 1 |
| Pirola, I | 1 |
| Agosti, B | 1 |
| Gandossi, E | 1 |
| Valentini, U | 1 |
| De Martino, E | 1 |
| Cimino, A | 1 |
| Chiovato, L | 1 |
| Agabiti-Rosei, E | 1 |
| Castellano, M | 1 |
| Mirouze, J | 1 |
| Jaffiol, C | 1 |
| Mary, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Metformin Versus Sitagliptin on Benign Thyroid Nodules Size in Type 2 Diabetes: a 2-years Prospective Multicentric Study[NCT04298684] | Phase 4 | 90 participants (Anticipated) | Interventional | 2021-01-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for metformin and Thyroid Diseases
| Article | Year |
|---|---|
Epidemiological, Pathophysiological, and Clinical Considerations on the Interplay between Thyroid Disorders and Type 2 Diabetes Mellitus.
Topics: Animals; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Metformin; Thyroid Diseases | 2023 |
Medical comorbidity in polycystic ovary syndrome with special focus on cardiometabolic, autoimmune, hepatic and cancer diseases: an updated review.
Topics: Body Mass Index; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Fatty Liver; Femal | 2017 |
Thyrovigilance in diabetes; glucovigilance in thyroidology.
Topics: Comorbidity; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Hypert | 2018 |
Endocrine basis for recurrent pregnancy loss.
Topics: Abortion, Habitual; Female; Humans; Hyperinsulinism; Hyperprolactinemia; Hypoglycemic Agents; Lutein | 2014 |
[Thyroid dysfunction in patients with type 2 diabetes mellitus].
Topics: Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Metf | 2014 |
Metformin and thyroid disease.
Topics: Humans; Hypoglycemic Agents; Metformin; Pituitary Gland; Thyroid Diseases; Thyroid Hormones; Thyrotr | 2017 |
1 trial available for metformin and Thyroid Diseases
| Article | Year |
|---|---|
TSH-lowering effect of metformin in type 2 diabetic patients: differences between euthyroid, untreated hypothyroid, and euthyroid on L-T4 therapy patients.
Topics: Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Hypothyroidism; Metformin; Thyroid Diseases; | 2009 |
2 other studies available for metformin and Thyroid Diseases
| Article | Year |
|---|---|
Association between worse metabolic control and increased thyroid volume and nodular disease in elderly adults with metabolic syndrome.
Topics: Aged; Aged, 80 and over; Anthropometry; Argentina; Body Mass Index; Cohort Studies; Cross-Sectional | 2015 |
[Extragonadal endocrine manifestations of Klinefelter's disease].
Topics: Adrenal Gland Diseases; Adult; Antibodies; Autoantibodies; Blood Glucose; Diabetes Mellitus; Diazoxi | 1973 |