metformin has been researched along with Thiamine Deficiency in 3 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Thiamine Deficiency: A nutritional condition produced by a deficiency of THIAMINE in the diet, characterized by anorexia, irritability, and weight loss. Later, patients experience weakness, peripheral neuropathy, headache, and tachycardia. In addition to being caused by a poor diet, thiamine deficiency in the United States most commonly occurs as a result of alcoholism, since ethanol interferes with thiamine absorption. In countries relying on polished rice as a dietary staple, BERIBERI prevalence is very high. (From Cecil Textbook of Medicine, 19th ed, p1171)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We herein report a case of cardiac dysfunction due to thiamine deficiency after hemodialysis in a patient with suspected biguanide-related lactic acidosis." | 8.12 | Cardiac Dysfunction Due to Thiamine Deficiency after Hemodialysis for Biguanide-related Lactic Acidosis. ( Jimura, F; Kachi, N; Tamaki, H; Tsushima, H, 2022) |
| " The significance of this topic has been illustrated by the recently established competition between thiamine and the antidiabetic drug metformin for common transporters, which can be the reason for the thiamine deficiency underlying metformin side effects." | 5.01 | Mechanisms of Non-coenzyme Action of Thiamine: Protein Targets and Medical Significance. ( Aleshin, VA; Bunik, VI; Mkrtchyan, GV, 2019) |
| " We herein report a case of cardiac dysfunction due to thiamine deficiency after hemodialysis in a patient with suspected biguanide-related lactic acidosis." | 4.12 | Cardiac Dysfunction Due to Thiamine Deficiency after Hemodialysis for Biguanide-related Lactic Acidosis. ( Jimura, F; Kachi, N; Tamaki, H; Tsushima, H, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Tamaki, H | 1 |
| Tsushima, H | 1 |
| Kachi, N | 1 |
| Jimura, F | 1 |
| Aleshin, VA | 1 |
| Mkrtchyan, GV | 1 |
| Bunik, VI | 1 |
| Alston, TA | 1 |
1 review available for metformin and Thiamine Deficiency
| Article | Year |
|---|---|
Mechanisms of Non-coenzyme Action of Thiamine: Protein Targets and Medical Significance.
Topics: Animals; Brain; Coenzymes; Humans; Hypoglycemic Agents; Metformin; Mice; Phosphorylation; Protein Tr | 2019 |
2 other studies available for metformin and Thiamine Deficiency
| Article | Year |
|---|---|
Cardiac Dysfunction Due to Thiamine Deficiency after Hemodialysis for Biguanide-related Lactic Acidosis.
Topics: Acidosis, Lactic; Beriberi; Biguanides; Diabetes Mellitus, Type 2; Heart Diseases; Humans; Hypoglyce | 2022 |
Does metformin interfere with thiamine?
Topics: Drug Interactions; Humans; Hypoglycemic Agents; Metformin; Thiamine; Thiamine Deficiency; Vitamin B | 2003 |