metformin has been researched along with Subarachnoid Hemorrhage in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
Excerpt | Relevance | Reference |
---|---|---|
"Metformin treatment after SAH promoted mitophagy in an AMPK-dependent manner." | 5.72 | Metformin attenuates early brain injury after subarachnoid hemorrhage in rats via AMPK-dependent mitophagy. ( Guo, Y; Li, Y; Liu, B; Shi, H; Tian, Y; Wu, P; Zhang, T; Zhang, Y, 2022) |
"Metformin treatment after SAH promoted mitophagy in an AMPK-dependent manner." | 1.72 | Metformin attenuates early brain injury after subarachnoid hemorrhage in rats via AMPK-dependent mitophagy. ( Guo, Y; Li, Y; Liu, B; Shi, H; Tian, Y; Wu, P; Zhang, T; Zhang, Y, 2022) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (50.00) | 2.80 |
Authors | Studies |
---|---|
Zhang, Y | 1 |
Zhang, T | 1 |
Li, Y | 1 |
Guo, Y | 1 |
Liu, B | 1 |
Tian, Y | 1 |
Wu, P | 1 |
Shi, H | 1 |
Jain, V | 1 |
Sharma, D | 1 |
Prabhakar, H | 1 |
Dash, HH | 1 |
2 other studies available for metformin and Subarachnoid Hemorrhage
Article | Year |
---|---|
Metformin attenuates early brain injury after subarachnoid hemorrhage in rats via AMPK-dependent mitophagy.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Blood-Brain Barrier; Brain Edema; Brain Injuries; | 2022 |
Metformin-associated lactic acidosis following contrast media-induced nephrotoxicity.
Topics: Acidosis, Lactic; Angiography, Digital Subtraction; Blood Gas Analysis; Contrast Media; Diabetes Mel | 2008 |