Page last updated: 2024-10-30

metformin and Starvation

metformin has been researched along with Starvation in 7 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Starvation: Lengthy and continuous deprivation of food. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"Although lactic acidosis has been recognized as a potential hazard in biguanide therapy, this complication has been claimed to be extremely rare with dimethylbiguanide (DMBG) (metformin)."7.66Metformin-induced lactic acidosis: potentiation by ethanol. ( Dubas, TC; Johnson, WJ, 1981)
"Although lactic acidosis has been recognized as a potential hazard in biguanide therapy, this complication has been claimed to be extremely rare with dimethylbiguanide (DMBG) (metformin)."3.66Metformin-induced lactic acidosis: potentiation by ethanol. ( Dubas, TC; Johnson, WJ, 1981)
"Cellular starvation is typically a consequence of tissue injury that disrupts the local blood supply but can also occur where cell populations outgrow the local vasculature, as observed in solid tumors."1.56Starvation and antimetabolic therapy promote cytokine release and recruitment of immune cells. ( Chevet, E; Eldering, E; Favaro, F; Iurlaro, R; Lucendo, E; Majem, B; Marchetti, S; Muñoz-Pinedo, C; Nadal, E; Püschel, F; Redondo-Pedraza, J; Ricci, JE, 2020)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Püschel, F1
Favaro, F1
Redondo-Pedraza, J1
Lucendo, E1
Iurlaro, R1
Marchetti, S1
Majem, B1
Eldering, E1
Nadal, E1
Ricci, JE1
Chevet, E1
Muñoz-Pinedo, C1
Hwang, SH1
Kim, MC1
Ji, S1
Yang, Y1
Jeong, Y1
Kim, Y1
Dubas, TC1
Johnson, WJ1
Large, V1
Beylot, M1
Debry, G1
Laurent, J1
Walker, RS1
Rigas, AN1
Bittles, AH1
Hadden, DR1
Montgomery, DA1

Trials

1 trial available for metformin and Starvation

ArticleYear
Circadian variation of glucose, insulin, and free fatty acids during long-term use of oral hypoglycaemic agents in diabetes mellitus.
    British medical journal, 1968, Oct-05, Volume: 4, Issue:5622

    Topics: Aged; Blood Glucose; Chlorpropamide; Circadian Rhythm; Diabetes Mellitus; Diet, Diabetic; Fatty Acid

1968

Other Studies

6 other studies available for metformin and Starvation

ArticleYear
Starvation and antimetabolic therapy promote cytokine release and recruitment of immune cells.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 05-05, Volume: 117, Issue:18

    Topics: Activating Transcription Factor 4; Antimetabolites; Cell Death; Deoxyglucose; Epithelial Cells; Gene

2020
Glucose starvation induces resistance to metformin through the elevation of mitochondrial multidrug resistance protein 1.
    Cancer science, 2019, Volume: 110, Issue:4

    Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Autophagy; Cell Line; Cell Proli

2019
Metformin-induced lactic acidosis: potentiation by ethanol.
    Research communications in chemical pathology and pharmacology, 1981, Volume: 33, Issue:1

    Topics: Acidosis; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Drug Synergism; Ethanol; Fasting;

1981
Modifications of citric acid cycle activity and gluconeogenesis in streptozotocin-induced diabetes and effects of metformin.
    Diabetes, 1999, Volume: 48, Issue:6

    Topics: Animals; Citric Acid Cycle; Diabetes Mellitus, Experimental; Gluconeogenesis; Glucose; Glutamic Acid

1999
[Lactic acidosis and sugar diabetics].
    Helvetica medica acta, 1970, Volume: 35, Issue:5

    Topics: Alcoholism; Diabetic Ketoacidosis; Humans; Hypoxia; Lactates; Metformin; Phenformin; Starvation

1970
Lactic acidosis through medicaments.
    Helvetica medica acta, 1970, Volume: 35, Issue:5

    Topics: Acetates; Acidosis; Animals; Culture Techniques; Diabetes Mellitus; Diabetic Ketoacidosis; Female; G

1970