metformin has been researched along with Sleep Apnea Syndromes in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Sleep Apnea Syndromes: Disorders characterized by multiple cessations of respirations during sleep that induce partial arousals and interfere with the maintenance of sleep. Sleep apnea syndromes are divided into central (see SLEEP APNEA, CENTRAL), obstructive (see SLEEP APNEA, OBSTRUCTIVE), and mixed central-obstructive types.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin is an efficient curative and preventive treatment for sleep apnea, suggesting that insulin resistance modifies the ventilatory drive independently of obesity." | 1.34 | Sleep apnea is induced by a high-fat diet and reversed and prevented by metformin in non-obese rats. ( Delanaud, S; Dewasmes, G; Geloen, A; Libert, JP; Petitjean, M; Ramadan, W; Wiernsperger, N, 2007) |
| "Metformin treatment, known to reduce insulin resistance, got sleep apnea scores back to their basic levels, reinforcing the idea that insulin resistance is a major factor in the occurrence of apneas in this rat model." | 1.33 | Effect of high-fat diet and metformin treatment on ventilation and sleep apnea in non-obese rats. ( Delanaud, S; Dewasmes, G; Geloen, A; Gros, F; Loos, N; Petitjean, M; Ramadan, W; Vardon, G, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ramadan, W | 2 |
| Petitjean, M | 2 |
| Loos, N | 1 |
| Geloen, A | 2 |
| Vardon, G | 1 |
| Delanaud, S | 2 |
| Gros, F | 1 |
| Dewasmes, G | 2 |
| Wiernsperger, N | 1 |
| Libert, JP | 1 |
2 other studies available for metformin and Sleep Apnea Syndromes
| Article | Year |
|---|---|
Effect of high-fat diet and metformin treatment on ventilation and sleep apnea in non-obese rats.
Topics: Analysis of Variance; Animals; Body Mass Index; Carbon Dioxide; Diabetes Mellitus; Dietary Fats; Dis | 2006 |
Sleep apnea is induced by a high-fat diet and reversed and prevented by metformin in non-obese rats.
Topics: Animals; Body Weight; Diet, Atherogenic; Dietary Fats; Drug Evaluation, Preclinical; Hypoglycemic Ag | 2007 |