metformin has been researched along with Sjogren's Syndrome in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Sjogren's Syndrome: Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin reduced salivary gland inflammation and restored the salivary flow rate." | 5.51 | Metformin improves salivary gland inflammation and hypofunction in murine Sjögren's syndrome. ( Cho, ML; Choi, J; Hwang, SH; Jung, KA; Kim, JW; Kim, SM; Kwok, SK; Lee, SY; Park, JS; Park, SH; Ryu, JG, 2019) |
| "Metformin reduced salivary gland inflammation and restored the salivary flow rate." | 1.51 | Metformin improves salivary gland inflammation and hypofunction in murine Sjögren's syndrome. ( Cho, ML; Choi, J; Hwang, SH; Jung, KA; Kim, JW; Kim, SM; Kwok, SK; Lee, SY; Park, JS; Park, SH; Ryu, JG, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, J | 1 |
| Kim, YS | 1 |
| Park, SH | 2 |
| Kim, JW | 1 |
| Kim, SM | 1 |
| Park, JS | 1 |
| Hwang, SH | 1 |
| Choi, J | 1 |
| Jung, KA | 1 |
| Ryu, JG | 1 |
| Lee, SY | 1 |
| Kwok, SK | 1 |
| Cho, ML | 1 |
1 review available for metformin and Sjogren's Syndrome
| Article | Year |
|---|---|
Metformin as a Treatment Strategy for Sjögren's Syndrome.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents, Non-Steroidal; B-Lymphocytes; Gast | 2021 |
1 other study available for metformin and Sjogren's Syndrome
| Article | Year |
|---|---|
Metformin improves salivary gland inflammation and hypofunction in murine Sjögren's syndrome.
Topics: Administration, Oral; Animals; B-Lymphocytes; Cell Differentiation; Cytokines; Disease Models, Anima | 2019 |