Page last updated: 2024-10-30

metformin and Shock

metformin has been researched along with Shock in 7 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Shock: A pathological condition manifested by failure to perfuse or oxygenate vital organs.

Research Excerpts

ExcerptRelevanceReference
"Metformin-associated lactic acidosis (MALA) is a rare complication among patients who are diabetic, commonly presenting with non-specific findings, and developing mostly among those with other risk factors for lactic acidosis."7.88Metformin-associated lactic acidosis mimicking ischaemic bowel. ( Ali, S; Azarov, N; Hindi, Z; Labuschagne, H; Oud, L, 2018)
"Metformin poisoning with lactic acidosis appears to be amenable to extracorporeal treatments."4.91Extracorporeal Treatment for Metformin Poisoning: Systematic Review and Recommendations From the Extracorporeal Treatments in Poisoning Workgroup. ( Calello, DP; Ghannoum, M; Gosselin, S; Hoffman, RS; Lavergne, V; Liu, KD; Nolin, TD; Roberts, DM; Wiegand, TJ, 2015)
"L-Carnitine combined with HDI may have helped with the calcium channel blocker (CCB) poisoning by decreasing insulin resistance, promoting intracellular glucose transport, facilitating the metabolism of free fatty acids, and increasing calcium channel sensitivity."4.89L-Carnitine for the treatment of a calcium channel blocker and metformin poisoning. ( Ajmo, I; Laliberté, M; Poirier, D; St-Onge, M, 2013)
"Metformin-associated lactic acidosis (MALA) is a rare complication among patients who are diabetic, commonly presenting with non-specific findings, and developing mostly among those with other risk factors for lactic acidosis."3.88Metformin-associated lactic acidosis mimicking ischaemic bowel. ( Ali, S; Azarov, N; Hindi, Z; Labuschagne, H; Oud, L, 2018)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (85.71)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Ali, S1
Labuschagne, H1
Azarov, N1
Hindi, Z1
Oud, L1
Trovato, FM1
Martines, GF1
Noto, P1
Mangano, G1
Malatino, L1
Carpinteri, G1
Schuenemeyer, JW1
Jette-Kelly, LA1
St-Onge, M1
Ajmo, I1
Poirier, D1
Laliberté, M1
Calello, DP1
Liu, KD1
Wiegand, TJ1
Roberts, DM1
Lavergne, V1
Gosselin, S1
Hoffman, RS1
Nolin, TD1
Ghannoum, M1
Graham, RE1
Cartner, M1
Winearls, J1
van den Nouland, DP1
Brouwers, MC1
Stassen, PM1

Reviews

2 reviews available for metformin and Shock

ArticleYear
L-Carnitine for the treatment of a calcium channel blocker and metformin poisoning.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2013, Volume: 9, Issue:3

    Topics: Aged; Antidotes; Antihypertensive Agents; Calcium Channel Blockers; Carnitine; Combined Modality The

2013
Extracorporeal Treatment for Metformin Poisoning: Systematic Review and Recommendations From the Extracorporeal Treatments in Poisoning Workgroup.
    Critical care medicine, 2015, Volume: 43, Issue:8

    Topics: Acidosis, Lactic; Consciousness; Delphi Technique; Humans; Hydrogen-Ion Concentration; Lactic Acid;

2015

Other Studies

5 other studies available for metformin and Shock

ArticleYear
Metformin-associated lactic acidosis mimicking ischaemic bowel.
    BMJ case reports, 2018, Feb-01, Volume: 2018

    Topics: Abdominal Pain; Acidosis, Lactic; Aged; Diabetes Mellitus; Diagnosis, Differential; Emergency Medica

2018
Metformin-associated lactic acidosis: Are we looking in the right direction?
    Diabetes & metabolism, 2020, Volume: 46, Issue:1

    Topics: Acidosis, Lactic; Acute Kidney Injury; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Metfo

2020
A 35-Year-Old Woman With Shock, Pulseless Electrical Activity Arrest, and Hemodynamic Collapse.
    Chest, 2019, Volume: 155, Issue:3

    Topics: Abdominal Pain; Acidosis, Lactic; Adult; Diabetes Mellitus, Type 2; Diagnosis, Differential; Drug-Re

2019
A severe case of vasoplegic shock following metformin overdose successfully treated with methylene blue as a last line therapy.
    BMJ case reports, 2015, Jul-06, Volume: 2015

    Topics: Acidosis; Adult; Drug Overdose; Fluid Therapy; Gliclazide; Humans; Male; Metformin; Methylene Blue;

2015
Prognostic value of plasma lactate levels in a retrospective cohort presenting at a university hospital emergency department.
    BMJ open, 2017, 01-30, Volume: 7, Issue:1

    Topics: Aged; Aged, 80 and over; Comorbidity; Diabetes Mellitus; Emergency Service, Hospital; Female; Hospit

2017