metformin has been researched along with Rhabdomyosarcoma in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Rhabdomyosarcoma: A malignant solid tumor arising from mesenchymal tissues which normally differentiate to form striated muscle. It can occur in a wide variety of sites. It is divided into four distinct types: pleomorphic, predominantly in male adults; alveolar (RHABDOMYOSARCOMA, ALVEOLAR), mainly in adolescents and young adults; embryonal (RHABDOMYOSARCOMA, EMBRYONAL), predominantly in infants and children; and botryoidal, also in young children. It is one of the most frequently occurring soft tissue sarcomas and the most common in children under 15. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p2186; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1647-9)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duan, C | 1 |
| Evison, A | 1 |
| Taylor, L | 1 |
| Onur, S | 1 |
| Morten, K | 1 |
| Townley, H | 1 |
| Garofalo, C | 1 |
| Capristo, M | 1 |
| Manara, MC | 1 |
| Mancarella, C | 1 |
| Landuzzi, L | 1 |
| Belfiore, A | 1 |
| Lollini, PL | 1 |
| Picci, P | 1 |
| Scotlandi, K | 1 |
2 other studies available for metformin and Rhabdomyosarcoma
| Article | Year |
|---|---|
The common diabetes drug metformin can diminish the action of citral against Rhabdomyosarcoma cells in vitro.
Topics: Acyclic Monoterpenes; Child; Humans; Hypoglycemic Agents; Medicine, Chinese Traditional; Metformin; | 2021 |
Metformin as an adjuvant drug against pediatric sarcomas: hypoxia limits therapeutic effects of the drug.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosi | 2013 |