metformin has been researched along with Retinoblastoma in 1 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Retinoblastoma: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Brodowska, K | 1 |
Theodoropoulou, S | 1 |
Meyer Zu Hörste, M | 1 |
Paschalis, EI | 1 |
Takeuchi, K | 1 |
Scott, G | 1 |
Ramsey, DJ | 1 |
Kiernan, E | 1 |
Hoang, M | 1 |
Cichy, J | 1 |
Miller, JW | 1 |
Gragoudas, ES | 1 |
Vavvas, DG | 1 |
1 other study available for metformin and Retinoblastoma
Article | Year |
---|---|
Effects of metformin on retinoblastoma growth in vitro and in vivo.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagy; Cell Proliferation; Gene Expression Re | 2014 |