Page last updated: 2024-10-30

metformin and Retinoblastoma

metformin has been researched along with Retinoblastoma in 1 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Retinoblastoma: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brodowska, K1
Theodoropoulou, S1
Meyer Zu Hörste, M1
Paschalis, EI1
Takeuchi, K1
Scott, G1
Ramsey, DJ1
Kiernan, E1
Hoang, M1
Cichy, J1
Miller, JW1
Gragoudas, ES1
Vavvas, DG1

Other Studies

1 other study available for metformin and Retinoblastoma

ArticleYear
Effects of metformin on retinoblastoma growth in vitro and in vivo.
    International journal of oncology, 2014, Volume: 45, Issue:6

    Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagy; Cell Proliferation; Gene Expression Re

2014