metformin has been researched along with Respiratory Distress Syndrome in 9 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Respiratory Distress Syndrome: A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA.
Excerpt | Relevance | Reference |
---|---|---|
"Metformin users were defined as those prescribed continuous oral metformin for ≥30 days before ARDS diagnosis." | 5.56 | Prior metformin therapy and 30-day mortality in patients with acute respiratory distress syndrome: a nationwide cohort study. ( Oh, TK; Song, IA, 2020) |
" We tested the drugs metformin (AMPK activator) and baicalin (CPT1A activator) in different experimental models mimicking COVID-19 associated inflammation in lung and kidney." | 4.31 | Enhanced fatty acid oxidation through metformin and baicalin as therapy for COVID-19 and associated inflammatory states in lung and kidney. ( Alcalde-Estévez, E; Castillo, C; Castro, A; Costa, IG; Fernández, L; Herrero, JI; Jansen, J; Kramann, R; Lamas, S; Miguel, V; Nagai, J; Ranz, I; Reimer, KC; Rey-Serra, C; Rodríguez González-Moro, JM; Sancho, D; Sevilla, L; Sirera, B; Tituaña, J, 2023) |
"Acute respiratory distress syndrome (ARDS), an inflammatory condition with high mortality rates, is common in severe COVID-19, whose risk is reduced by metformin rather than other anti-diabetic medications." | 4.02 | Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation. ( Aleman-Muench, GR; Arditi, M; Chen, W; Crother, TR; de la Torre, JC; Gatchalian, R; Kang, S; Karin, M; Lewis, G; Lipton, SA; Liu, Y; Luevanos, M; Rundberg Nilsson, A; Sanchez-Lopez, E; Soroosh, P; Teijaro, J; Tourtellotte, WG; Trudler, D; Xian, H; Zhang, Y, 2021) |
"Of 328 patients with COVID-19 and type 2 diabetes included in the study cohort, 30." | 1.62 | Association of metformin with mortality or ARDS in patients with COVID-19 and type 2 diabetes: A retrospective cohort study. ( Chen, Z; Gong, Y; Jiang, N; Li, H; Liu, L; Lu, Z; Tan, X; Tian, M; Wang, J; Xiong, N; Yang, H; Yin, X, 2021) |
"Metformin users were defined as those prescribed continuous oral metformin for ≥30 days before ARDS diagnosis." | 1.56 | Prior metformin therapy and 30-day mortality in patients with acute respiratory distress syndrome: a nationwide cohort study. ( Oh, TK; Song, IA, 2020) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (22.22) | 29.6817 |
2010's | 1 (11.11) | 24.3611 |
2020's | 6 (66.67) | 2.80 |
Authors | Studies |
---|---|
Miguel, V | 1 |
Rey-Serra, C | 1 |
Tituaña, J | 1 |
Sirera, B | 1 |
Alcalde-Estévez, E | 1 |
Herrero, JI | 1 |
Ranz, I | 1 |
Fernández, L | 1 |
Castillo, C | 1 |
Sevilla, L | 1 |
Nagai, J | 1 |
Reimer, KC | 1 |
Jansen, J | 1 |
Kramann, R | 1 |
Costa, IG | 1 |
Castro, A | 1 |
Sancho, D | 1 |
Rodríguez González-Moro, JM | 1 |
Lamas, S | 1 |
Oh, TK | 1 |
Song, IA | 1 |
Nguépy Keubo, FR | 1 |
Mboua, PC | 1 |
Djifack Tadongfack, T | 1 |
Fokouong Tchoffo, E | 1 |
Tasson Tatang, C | 1 |
Ide Zeuna, J | 1 |
Noupoue, EM | 1 |
Tsoplifack, CB | 1 |
Folefack, GO | 1 |
Kettani, M | 1 |
Bandelier, P | 1 |
Huo, J | 1 |
Li, H | 5 |
Yu, D | 1 |
Arulsamy, N | 1 |
AlAbbad, S | 1 |
Sardot, T | 1 |
Lekashvili, O | 1 |
Decato, D | 1 |
Lelj, F | 1 |
Alexander Ross, JB | 1 |
Rosenberg, E | 1 |
Nazir, H | 1 |
Muthuswamy, N | 1 |
Louis, C | 1 |
Jose, S | 1 |
Prakash, J | 1 |
Buan, MEM | 1 |
Flox, C | 1 |
Chavan, S | 1 |
Shi, X | 1 |
Kauranen, P | 1 |
Kallio, T | 1 |
Maia, G | 1 |
Tammeveski, K | 1 |
Lymperopoulos, N | 1 |
Carcadea, E | 1 |
Veziroglu, E | 1 |
Iranzo, A | 1 |
M Kannan, A | 1 |
Arunamata, A | 1 |
Tacy, TA | 1 |
Kache, S | 1 |
Mainwaring, RD | 1 |
Ma, M | 1 |
Maeda, K | 1 |
Punn, R | 1 |
Noguchi, S | 1 |
Hahn, S | 3 |
Iwasa, Y | 3 |
Ling, J | 2 |
Voccio, JP | 2 |
Kim, Y | 3 |
Song, J | 3 |
Bascuñán, J | 2 |
Chu, Y | 1 |
Tomita, M | 1 |
Cazorla, M | 1 |
Herrera, E | 1 |
Palomeque, E | 1 |
Saud, N | 1 |
Hoplock, LB | 1 |
Lobchuk, MM | 1 |
Lemoine, J | 1 |
Li, X | 10 |
Henson, MA | 1 |
Unsihuay, D | 1 |
Qiu, J | 1 |
Swaroop, S | 1 |
Nagornov, KO | 1 |
Kozhinov, AN | 1 |
Tsybin, YO | 1 |
Kuang, S | 1 |
Laskin, J | 1 |
Zin, NNINM | 1 |
Mohamad, MN | 1 |
Roslan, K | 1 |
Abdul Wafi, S | 1 |
Abdul Moin, NI | 1 |
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Zakaria, Y | 1 |
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Li, XY | 1 |
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Fan, XH | 1 |
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Liu, ZM | 1 |
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Xing, YL | 1 |
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Neradilek, MB | 1 |
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Huang, W | 1 |
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1 review available for metformin and Respiratory Distress Syndrome
Article | Year |
---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
1 trial available for metformin and Respiratory Distress Syndrome
Article | Year |
---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
8 other studies available for metformin and Respiratory Distress Syndrome
Article | Year |
---|---|
Enhanced fatty acid oxidation through metformin and baicalin as therapy for COVID-19 and associated inflammatory states in lung and kidney.
Topics: AMP-Activated Protein Kinases; Animals; COVID-19; Fatty Acids; Fibrosis; Humans; Inflammation; Kidne | 2023 |
Prior metformin therapy and 30-day mortality in patients with acute respiratory distress syndrome: a nationwide cohort study.
Topics: Adult; Cohort Studies; Diabetes Mellitus; Humans; Metformin; Proportional Hazards Models; Republic o | 2020 |
Metformin in acute respiratory distress syndrome: An opinion.
Topics: Animals; Cattle; COVID-19; Endothelial Cells; Humans; Lung; Metformin; Respiratory Distress Syndrome | 2021 |
Association of metformin with mortality or ARDS in patients with COVID-19 and type 2 diabetes: A retrospective cohort study.
Topics: Aged; China; Cohort Studies; COVID-19; Diabetes Mellitus, Type 2; Female; Hospitalization; Humans; M | 2021 |
Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation.
Topics: Adenosine Triphosphate; Animals; COVID-19; Cytokines; DNA, Mitochondrial; Humans; Inflammasomes; Int | 2021 |
Metformin-stimulated AMPK-α1 promotes microvascular repair in acute lung injury.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cell Membrane Permeability; Cell | 2013 |
Metformin-associated lactic acidosis following contrast media-induced nephrotoxicity.
Topics: Acidosis, Lactic; Angiography, Digital Subtraction; Blood Gas Analysis; Contrast Media; Diabetes Mel | 2008 |
Mitochondrial respiratory complex I regulates neutrophil activation and severity of lung injury.
Topics: Animals; Cytokines; Electron Transport Complex I; Hypoglycemic Agents; Lipopolysaccharides; Male; Me | 2008 |