Page last updated: 2024-10-30

metformin and Recrudescence

metformin has been researched along with Recrudescence in 32 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Research Excerpts

ExcerptRelevanceReference
"To determine the effectiveness and safety of metformin in treating women with endometrial hyperplasia."8.95Metformin for endometrial hyperplasia. ( Atiomo, W; Clement, NS; Mulvaney, CA; Oliver, TR; Sanner, JR; Shiwani, H, 2017)
"Metformin toxicity is well known to cause lactic acidosis."7.88Recurrent hypoglycemia secondary to metformin toxicity in the absence of co-ingestions: a case report. ( Aldobeaban, S; Alshehri, AA; Mzahim, B, 2018)
"Metformin therapy in pregnant women with PCOS was associated with a significant reduction in the rate of early pregnancy loss."7.81Effect of metformin on early pregnancy loss in women with polycystic ovary syndrome. ( Al-Biate, MA, 2015)
"The impact of diabetes mellitus (DM) and metformin use on biochemical recurrence (BCR) in patients treated with radical prostatectomy (RP) remains controversial."7.80Association of diabetes mellitus and metformin use with biochemical recurrence in patients treated with radical prostatectomy for prostate cancer. ( Bachmann, A; Becker, A; Faison, T; Fajkovic, H; Herman, M; Karakiewicz, PI; Kautzky-Willer, A; Kluth, LA; Lee, RK; Loidl, W; Lotan, Y; Pummer, K; Remzi, M; Rieken, M; Scherr, DS; Schramek, P; Seitz, C; Shariat, SF; Tewari, A; Xylinas, E, 2014)
"Metformin has been shown to prevent insulin therapy-induced body weight gain when used in combination with insulin."6.70Metformin does not adversely affect hormonal and symptomatic responses to recurrent hypoglycemia. ( Born, J; Fehm, HL; Fruehwald-Schultes, B; Kern, W; Oltmanns, KM; Peters, A; Sopke, S; Toschek, B, 2001)
"To determine the effectiveness and safety of metformin in treating women with endometrial hyperplasia."4.95Metformin for endometrial hyperplasia. ( Atiomo, W; Clement, NS; Mulvaney, CA; Oliver, TR; Sanner, JR; Shiwani, H, 2017)
"Metformin toxicity is well known to cause lactic acidosis."3.88Recurrent hypoglycemia secondary to metformin toxicity in the absence of co-ingestions: a case report. ( Aldobeaban, S; Alshehri, AA; Mzahim, B, 2018)
"Metformin therapy in pregnant women with PCOS was associated with a significant reduction in the rate of early pregnancy loss."3.81Effect of metformin on early pregnancy loss in women with polycystic ovary syndrome. ( Al-Biate, MA, 2015)
"The impact of diabetes mellitus (DM) and metformin use on biochemical recurrence (BCR) in patients treated with radical prostatectomy (RP) remains controversial."3.80Association of diabetes mellitus and metformin use with biochemical recurrence in patients treated with radical prostatectomy for prostate cancer. ( Bachmann, A; Becker, A; Faison, T; Fajkovic, H; Herman, M; Karakiewicz, PI; Kautzky-Willer, A; Kluth, LA; Lee, RK; Loidl, W; Lotan, Y; Pummer, K; Remzi, M; Rieken, M; Scherr, DS; Schramek, P; Seitz, C; Shariat, SF; Tewari, A; Xylinas, E, 2014)
"Metformin was administered twice daily for 28 days in addition to vincristine, dexamethasone, PEG-asparaginase and doxorubicin (VXLD)."2.87A phase I window, dose escalating and safety trial of metformin in combination with induction chemotherapy in relapsed refractory acute lymphoblastic leukemia: Metformin with induction chemotherapy of vincristine, dexamethasone, PEG-asparaginase, and doxo ( Barredo, JC; Gill, J; Goldberg, J; Hale, GA; Leclerc, GM; Lee, JK; Lush, R; Reed, DR; Setty, B; Smith, T; Trucco, M, 2018)
"Metformin has been shown to prevent insulin therapy-induced body weight gain when used in combination with insulin."2.70Metformin does not adversely affect hormonal and symptomatic responses to recurrent hypoglycemia. ( Born, J; Fehm, HL; Fruehwald-Schultes, B; Kern, W; Oltmanns, KM; Peters, A; Sopke, S; Toschek, B, 2001)
" Although no studies have been performed, anti-tuberculosis treatment may also have to be prolonged or intensified in terms of regimen or drug dosage if DM is present."2.58Clinical management of combined tuberculosis and diabetes. ( Harries, AD; Hill, PC; Koesoemadinata, R; van Crevel, R, 2018)
"One of the medical treatments used in Cushing's disease is the somatostatin analogue pasireotide, which acts on adrenocorticotropic hormone (ACTH) secretion by the pituitary."2.49Management of hyperglycaemia in Cushing's disease: experts' proposals on the use of pasireotide. ( Bertherat, J; Bisot-Locard, S; Borson-Chazot, F; Brue, T; Chanson, P; Cortet-Rudelli, C; Delemer, B; Reznik, Y; Tabarin, A; Vergès, B, 2013)
"The effects of type 2 diabetes mellitus (T2DM) medications on secondary prevention after acute coronary syndrome (ACS) remain unclear."1.56Recurrent cardiovascular events in patients with newly diagnosed acute coronary syndrome: Influence of diabetes and its management with medication. ( Asano, T; Komaru, Y; Suzuki, L; Takeuchi, T; Urayama, KY, 2020)
"Metformin treatment relieves the clinical symptoms, reduces the inflammatory reaction indexes and regulates the Treg/Th17 axis in patients with BD, suggesting the potential of metformin as a candidate medicine for treatment of BD."1.51[Efficacy and safety of metformin for Behcet's disease and its effect on Treg/Th17 balance: a single-blinded, before-after study]. ( Chenhong, L; Dan, L; Jianfei, C; Jianlong, G; Yan, S; Yong, C, 2019)
"Metformin has antineoplastic and cancer protective effects in vitro, sensitizing leukemia cells to chemotherapeutic agents, inducing apoptosis and cell cycle arrest."1.48[Effect of metformin added to chemotherapy on the survival of patients with acute lymphoblastic leukemia]. ( Centeno Cruz, F; Ceron Maldonado, R; Collazo Jaloma, J; Kassack Ipiña, JJ; Martínez Tovar, A; Miranda Peralta, E; Olarte Carrillo, I; Ramos Peñafiel, C; Rozen Fuller, E, 2018)
"A total of 543 rectal cancer patients who were treated with neoadjuvant chemoradiotherapy followed by radical surgery from January 2007 to December 2011 were reviewed."1.43Metformin enhances the response to radiotherapy in diabetic patients with rectal cancer. ( Cho, YB; Choi, DH; Huh, JW; Kim, HC; Lee, WY; Oh, BY; Park, HC; Park, YA; Park, YS; Yun, SH, 2016)
"In her fifth pregnancy, treatment for gestational diabetes mellitus with metformin was associated with a lowering effect on bile acids and liver enzymes, indicating a possible role for metformin in the management of obstetric cholestasis."1.43Managing Recurring Obstetric Cholestasis With Metformin. ( Ali, A; Elfituri, A; Shehata, H, 2016)
"Postpericardiotomy syndrome is a well-known complication after cardiac surgery."1.42Incidence and risk factors of postpericardiotomy syndrome requiring medical attention: The Finland postpericardiotomy syndrome study. ( Airaksinen, J; Gunn, J; Karjalainen, P; Kiviniemi, T; Lehto, J, 2015)
"We identified 4817 stroke patients with type 2 diabetes mellitus."1.38Type of preadmission antidiabetic treatment and outcome among patients with ischemic stroke: a nationwide follow-up study. ( Horsdal, HT; Johnsen, SP; Mehnert, F; Rungby, J, 2012)
" Metformin, the first-line drug for diabetes, has low bioavailability and slow, incomplete gastrointestinal absorption."1.37Effect of gastric bypass surgery on the absorption and bioavailability of metformin. ( Birch, DW; Brocks, DR; Gabr, RQ; Karmali, S; Langkaas, LA; Padwal, RS; Sharma, AM, 2011)
" After reduction of the metformin dosage (500 mg twice daily) and discontinuance of exenatide as well as a reduction of his physical activity (because of joint pain) for six months, the glucose control worsened."1.36[Sequential treatment with insulin glargine and metformin, and exenatide in a patient with newly diagnosed type-2 diabetes]. ( Kress, S, 2010)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (12.50)29.6817
2010's24 (75.00)24.3611
2020's4 (12.50)2.80

Authors

AuthorsStudies
Komaru, Y1
Takeuchi, T1
Suzuki, L1
Asano, T1
Urayama, KY1
McInnes, N1
Hall, S1
Sultan, F1
Aronson, R1
Hramiak, I1
Harris, S1
Sigal, RJ1
Woo, V1
Liu, YY1
Gerstein, HC1
Kopel, J1
Grooms, A1
Ganapathy, V1
Clothier, J1
Deshmukh, A1
Ghannam, M1
Liang, J1
Saeed, M1
Cunnane, R1
Ghanbari, H1
Latchamsetty, R1
Crawford, T1
Batul, SA1
Chung, E1
Bogun, F1
Jongnarangsin, K1
Pelosi, F1
Chugh, A1
Morady, F1
Oral, E1
Oral, H1
Dutta, NK1
Pinn, ML1
Karakousis, PC1
Clement, NS1
Oliver, TR1
Shiwani, H1
Sanner, JR1
Mulvaney, CA1
Atiomo, W1
Trucco, M1
Barredo, JC1
Goldberg, J1
Leclerc, GM1
Hale, GA1
Gill, J1
Setty, B1
Smith, T1
Lush, R1
Lee, JK1
Reed, DR1
Aldobeaban, S1
Mzahim, B1
Alshehri, AA1
Ramos Peñafiel, C1
Olarte Carrillo, I1
Ceron Maldonado, R1
Miranda Peralta, E1
Rozen Fuller, E1
Kassack Ipiña, JJ1
Centeno Cruz, F1
Collazo Jaloma, J1
Martínez Tovar, A1
van Crevel, R1
Koesoemadinata, R1
Hill, PC1
Harries, AD1
Yong, C1
Dan, L1
Chenhong, L1
Yan, S1
Jianfei, C1
Jianlong, G1
Kibrik, P1
Alsheekh, A1
Izakovich, T1
Chait, J1
Goldstein, MA1
Monteleone, CM1
Hingorani, A1
Ascher, E1
Rieken, M1
Kluth, LA1
Xylinas, E1
Fajkovic, H1
Becker, A1
Karakiewicz, PI1
Herman, M1
Lotan, Y1
Seitz, C1
Schramek, P1
Remzi, M1
Loidl, W1
Pummer, K1
Lee, RK1
Faison, T1
Scherr, DS1
Kautzky-Willer, A1
Bachmann, A1
Tewari, A1
Shariat, SF1
Nicolle, LE1
Capuano, G1
Fung, A1
Usiskin, K1
Greenhill, C1
Lehto, J1
Gunn, J1
Karjalainen, P1
Airaksinen, J1
Kiviniemi, T1
Béjot, Y1
Bielefeld, P1
Guiboux, AL1
Sgro, C1
Janoura, S1
Devilliers, H1
Besancenot, JF1
Giroud, M1
Lefaucheur, R1
Bourre, B1
Ozkul-Wermester, O1
Maltête, D1
Wallon, D1
Al-Biate, MA1
Oh, BY1
Park, YA1
Huh, JW1
Cho, YB1
Yun, SH1
Lee, WY1
Park, HC1
Choi, DH1
Park, YS1
Kim, HC1
Elfituri, A1
Ali, A1
Shehata, H1
Kress, S1
Boehm, KM1
Gunaga, S1
Patel, T1
Hruby, G1
Badani, K1
Abate-Shen, C1
McKiernan, JM1
Padwal, RS1
Gabr, RQ1
Sharma, AM1
Langkaas, LA1
Birch, DW1
Karmali, S1
Brocks, DR1
Horsdal, HT1
Mehnert, F1
Rungby, J1
Johnsen, SP1
Panossian, Z1
Drury, PL1
Cundy, T1
Reznik, Y1
Bertherat, J1
Borson-Chazot, F1
Brue, T1
Chanson, P1
Cortet-Rudelli, C1
Delemer, B1
Tabarin, A1
Bisot-Locard, S1
Vergès, B1
Heine, RJ1
Diamant, M1
Mbanya, JC1
Nathan, DM1
Mellbin, LG1
Malmberg, K1
Norhammar, A1
Wedel, H1
Rydén, L1
Fruehwald-Schultes, B1
Kern, W1
Oltmanns, KM1
Sopke, S1
Toschek, B1
Born, J1
Fehm, HL1
Peters, A1
Lee, F1
Patel, HR1
Copland, P1
Kahn, L1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Remission Evaluation of a Metabolic Intervention in Type 2 Diabetes With Forxiga[NCT02561130]Phase 4154 participants (Actual)Interventional2015-12-31Completed
Effect of Metformin on ABCB1 and AMPK Expression in Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia[NCT05326984]20 participants (Anticipated)Interventional2021-02-09Recruiting
METformin in Intrahepatic Cholestasis of Pregnancy (METRIC) Study[NCT03056274]Phase 2/Phase 340 participants (Anticipated)Interventional2019-01-31Not yet recruiting
Study of the Concentrations of Long Acting Morphine After Oral Absorption in Subjects Who Underwent Gastric Bypass (OBEMO 2)[NCT02641301]Phase 424 participants (Actual)Interventional2015-12-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Waist Circumference From Baseline

(Waist circumference at 12 weeks - waist circumference at randomization) (NCT02561130)
Timeframe: 12 weeks after randomization

Interventioncm (Mean)
Intervention-3.0
Standard Care-1.3

Glycated Hemoglobin (HbA1C)

Expressed in Diabetes Control and Complications Trial (DCCT) units (NCT02561130)
Timeframe: 12 weeks after randomization

Interventionpercentage of glycated hemoglobin (Mean)
Intervention5.9
Standard Care6.6

Number of Participants Achieving Diabetes Relapse Without Overt Hyperglycemia Off Diabetes Drugs

Diabetes relapse without overt hyperglycemia is defined as HbA1C 6.5-6.9% off glucose-lowering agents for at least 12 weeks. (NCT02561130)
Timeframe: 24 weeks

InterventionParticipants (Count of Participants)
Intervention20
Standard Care9

Number of Participants Achieving Drug-free Diabetes Remission

Drug-free diabetes remission is defined as HbA1C < 6.5 % off glucose-lowering agents for at least 12 weeks. (NCT02561130)
Timeframe: 64 weeks after randomization

InterventionParticipants (Count of Participants)
Intervention11
Standard Care6

Number of Participants Achieving Drug-free Diabetes Remission in the Experimental Group Compared to the Control Group

Drug-free diabetes remission is defined as HbA1C < 6.5 % off glucose-lowering agents for at least 12 weeks. (NCT02561130)
Timeframe: 24 weeks after randomization

InterventionParticipants (Count of Participants)
Intervention19
Standard Care13

Number of Participants Achieving Drug-free HbA1C < 6.0%

Drug-free complete diabetes remission is defined as HbA1C < 6.0 % off glucose-lowering agents for at least 12 weeks. (NCT02561130)
Timeframe: 24 weeks after randomization

InterventionParticipants (Count of Participants)
Intervention6
Standard Care6

Number of Participants With Non-severe Symptomatic Hypoglycemic Episodes

Symptomatic hypoglycemic episode is defined as an event with clinical symptoms consistent with hypoglycemia. (NCT02561130)
Timeframe: During 64 weeks of follow-up

InterventionParticipants (Count of Participants)
Intervention34
Standard Care15

Number of Participants With Severe Hypoglycemic Episodes

Severe hypoglycemic episode is defined as an event with clinical symptoms consistent with hypoglycemia in which the participant required the assistance of another person, and one of the following: (i) the event was associated with a documented self-measured or laboratory plasma glucose level NCT02561130)
Timeframe: During 64 weeks of follow-up

InterventionParticipants (Count of Participants)
Intervention0
Standard Care0

Percentage of Weight Loss From Baseline

(Weight at randomization - weight at 12 weeks)/(weight at randomization) (NCT02561130)
Timeframe: 12 weeks after randomization

Interventionpercentage of weight loss (Mean)
Intervention2.9
Standard Care1.0

Reviews

4 reviews available for metformin and Recrudescence

ArticleYear
Metformin for endometrial hyperplasia.
    The Cochrane database of systematic reviews, 2017, Oct-27, Volume: 10

    Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Disease Progression; Endometrial Hyperplasia; Female;

2017
Clinical management of combined tuberculosis and diabetes.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2018, 12-01, Volume: 22, Issue:12

    Topics: Antitubercular Agents; Diabetes Mellitus, Type 2; Drug Interactions; Humans; Hypoglycemic Agents; Me

2018
Management of hyperglycaemia in Cushing's disease: experts' proposals on the use of pasireotide.
    Diabetes & metabolism, 2013, Volume: 39, Issue:1

    Topics: Biomarkers; Blood Glucose; Clinical Trials as Topic; Drug Therapy, Combination; Glycated Hemoglobin;

2013
Management of hyperglycaemia in type 2 diabetes: the end of recurrent failure?
    BMJ (Clinical research ed.), 2006, Dec-09, Volume: 333, Issue:7580

    Topics: Algorithms; Diabetes Mellitus, Type 2; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin-

2006

Trials

5 trials available for metformin and Recrudescence

ArticleYear
Remission of Type 2 Diabetes Following a Short-term Intervention With Insulin Glargine, Metformin, and Dapagliflozin.
    The Journal of clinical endocrinology and metabolism, 2020, 08-01, Volume: 105, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Type 2; Drug

2020
A phase I window, dose escalating and safety trial of metformin in combination with induction chemotherapy in relapsed refractory acute lymphoblastic leukemia: Metformin with induction chemotherapy of vincristine, dexamethasone, PEG-asparaginase, and doxo
    Pediatric blood & cancer, 2018, Volume: 65, Issue:9

    Topics: Adolescent; AMP-Activated Protein Kinases; Antineoplastic Combined Chemotherapy Protocols; Asparagin

2018
Urinary tract infection in randomized phase III studies of canagliflozin, a sodium glucose co-transporter 2 inhibitor.
    Postgraduate medicine, 2014, Volume: 126, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Glucose; Blood Pressure; Body Weight; Canagliflozi

2014
The impact of glucose lowering treatment on long-term prognosis in patients with type 2 diabetes and myocardial infarction: a report from the DIGAMI 2 trial.
    European heart journal, 2008, Volume: 29, Issue:2

    Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Epidemiologic Methods; Female; Humans; Hypoglycemic

2008
Metformin does not adversely affect hormonal and symptomatic responses to recurrent hypoglycemia.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:9

    Topics: Adult; Area Under Curve; Autonomic Nervous System; Blood Glucose; Double-Blind Method; Glucose Clamp

2001

Other Studies

23 other studies available for metformin and Recrudescence

ArticleYear
Recurrent cardiovascular events in patients with newly diagnosed acute coronary syndrome: Influence of diabetes and its management with medication.
    Journal of diabetes and its complications, 2020, Volume: 34, Issue:3

    Topics: Acute Coronary Syndrome; Aged; Cardiovascular Diseases; Cohort Studies; Diabetes Mellitus, Type 2; F

2020
Metformin, valproic acid, and starvation induce seizures in a patient with partial SLC13A5 deficiency: a case of pharmaco-synergistic heterozygosity.
    Psychiatric genetics, 2021, 02-01, Volume: 31, Issue:1

    Topics: Adult; Amino Acid Substitution; Ammonia; Animals; Anticonvulsants; Autistic Disorder; Bipolar Disord

2021
Effect of metformin on outcomes of catheter ablation for atrial fibrillation.
    Journal of cardiovascular electrophysiology, 2021, Volume: 32, Issue:5

    Topics: Aged; Atrial Fibrillation; Catheter Ablation; Female; Humans; Metformin; Middle Aged; Recurrence; Ri

2021
Metformin Adjunctive Therapy Does Not Improve the Sterilizing Activity of the First-Line Antitubercular Regimen in Mice.
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:8

    Topics: Animals; Antitubercular Agents; Bacterial Load; Disease Models, Animal; Drug Synergism; Drug Therapy

2017
Recurrent hypoglycemia secondary to metformin toxicity in the absence of co-ingestions: a case report.
    Journal of medical case reports, 2018, Aug-18, Volume: 12, Issue:1

    Topics: Acidosis, Lactic; Anti-Obesity Agents; Female; Humans; Hypoglycemia; Metformin; Polycystic Ovary Syn

2018
[Effect of metformin added to chemotherapy on the survival of patients with acute lymphoblastic leukemia].
    Revista medica de Chile, 2018, Volume: 146, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; D

2018
[Efficacy and safety of metformin for Behcet's disease and its effect on Treg/Th17 balance: a single-blinded, before-after study].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2019, 02-28, Volume: 39, Issue:2

    Topics: Behcet Syndrome; Controlled Before-After Studies; Forkhead Transcription Factors; Humans; Immunosupp

2019
Does Metformin Have an Effect on Stent Patency Rates.
    Vascular and endovascular surgery, 2019, Volume: 53, Issue:6

    Topics: Aged; Constriction, Pathologic; Diabetes Mellitus, Type 2; Endovascular Procedures; Female; Femoral

2019
Association of diabetes mellitus and metformin use with biochemical recurrence in patients treated with radical prostatectomy for prostate cancer.
    World journal of urology, 2014, Volume: 32, Issue:4

    Topics: Aged; Diabetes Mellitus; Follow-Up Studies; Humans; Hypoglycemic Agents; Insulin-Like Growth Factor

2014
Gastric cancer. Metformin improves survival and recurrence rate in patients with diabetes and gastric cancer.
    Nature reviews. Gastroenterology & hepatology, 2015, Volume: 12, Issue:3

    Topics: Antineoplastic Agents; Chemotherapy, Adjuvant; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agent

2015
Incidence and risk factors of postpericardiotomy syndrome requiring medical attention: The Finland postpericardiotomy syndrome study.
    The Journal of thoracic and cardiovascular surgery, 2015, Volume: 149, Issue:5

    Topics: Aged; Body Mass Index; Chi-Square Distribution; Comorbidity; Diabetes Mellitus; Drainage; Erythrocyt

2015
Recurrent encephalopathy induced by metformin in an elderly man.
    Journal of the American Geriatrics Society, 2015, Volume: 63, Issue:3

    Topics: Aged; Brain Diseases; Humans; Male; Metformin; Recurrence

2015
Stroke mimicking relapse in a patient with CLIPPERS syndrome.
    Acta neurologica Belgica, 2015, Volume: 115, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Aspirin; Brain Stem; Encephalomye

2015
Effect of metformin on early pregnancy loss in women with polycystic ovary syndrome.
    Taiwanese journal of obstetrics & gynecology, 2015, Volume: 54, Issue:3

    Topics: Abortion, Spontaneous; Adult; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndr

2015
Metformin enhances the response to radiotherapy in diabetic patients with rectal cancer.
    Journal of cancer research and clinical oncology, 2016, Volume: 142, Issue:6

    Topics: Aged; Case-Control Studies; Chemoradiotherapy; Diabetes Complications; Female; Humans; Hypoglycemic

2016
Managing Recurring Obstetric Cholestasis With Metformin.
    Obstetrics and gynecology, 2016, Volume: 128, Issue:6

    Topics: Adult; Bile Acids and Salts; Cholagogues and Choleretics; Cholestasis, Intrahepatic; Diabetes, Gesta

2016
[Sequential treatment with insulin glargine and metformin, and exenatide in a patient with newly diagnosed type-2 diabetes].
    Deutsche medizinische Wochenschrift (1946), 2010, Volume: 135, Issue:18

    Topics: Blood Glucose; Combined Modality Therapy; Diabetes Mellitus, Type 2; Dose-Response Relationship, Dru

2010
Cimetidine-induced lactic acidosis and acute pancreatitis.
    Southern medical journal, 2010, Volume: 103, Issue:8

    Topics: Acidosis, Lactic; Acute Disease; Cimetidine; Diabetes Mellitus, Type 2; Drug Interactions; Female; G

2010
Clinical outcomes after radical prostatectomy in diabetic patients treated with metformin.
    Urology, 2010, Volume: 76, Issue:5

    Topics: Aged; Antineoplastic Agents; Diabetes Mellitus, Type 2; Disease-Free Survival; Humans; Hypoglycemic

2010
Effect of gastric bypass surgery on the absorption and bioavailability of metformin.
    Diabetes care, 2011, Volume: 34, Issue:6

    Topics: Absorption; Adolescent; Adult; Area Under Curve; Biological Availability; Diabetes Mellitus; Female;

2011
Type of preadmission antidiabetic treatment and outcome among patients with ischemic stroke: a nationwide follow-up study.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2012, Volume: 21, Issue:8

    Topics: Aged; Aged, 80 and over; Brain Ischemia; Denmark; Diabetes Mellitus, Type 2; Female; Follow-Up Studi

2012
Reversible severe deterioration of glycaemic control after withdrawal of metformin treatment.
    Diabetologia, 2012, Volume: 55, Issue:1

    Topics: Aged; Aged, 80 and over; Contraindications; Diabetes Complications; Diabetes Mellitus, Type 2; Drug

2012
Fowler's syndrome: cause or consequence of insulin resistance?
    BJU international, 2002, Volume: 89, Issue:1

    Topics: Adult; Electromyography; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Polycys

2002