metformin has been researched along with Primary Peritonitis in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition to their effects on chemotaxis, treatment of neutrophils with metformin or aminoimidazole carboxamide ribonucleotide (AICAR) improved phagocytosis and bacterial killing, including more efficient eradication of bacteria in a mouse model of peritonitis-induced sepsis." | 3.79 | Activation of AMPK enhances neutrophil chemotaxis and bacterial killing. ( Abraham, E; Deshane, J; Gao, Y; Jiang, S; Park, DW; Stigler, WS; Tadie, JM; Zmijewski, JW, 2013) |
| "Mast cells are major effectors of allergy and asthma, and can be activated by the alarmin IL-33, which is linked to allergic disease." | 1.48 | Inhibiting Glycolysis and ATP Production Attenuates IL-33-Mediated Mast Cell Function and Peritonitis. ( Baldwin, EA; Barnstein, BO; Caslin, HL; Haque, T; Pondicherry, N; Ryan, JJ; Taruselli, MT, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Caslin, HL | 1 |
| Taruselli, MT | 1 |
| Haque, T | 1 |
| Pondicherry, N | 1 |
| Baldwin, EA | 1 |
| Barnstein, BO | 1 |
| Ryan, JJ | 1 |
| Park, DW | 1 |
| Jiang, S | 1 |
| Tadie, JM | 1 |
| Stigler, WS | 1 |
| Gao, Y | 1 |
| Deshane, J | 1 |
| Abraham, E | 1 |
| Zmijewski, JW | 1 |
2 other studies available for metformin and Primary Peritonitis
| Article | Year |
|---|---|
Inhibiting Glycolysis and ATP Production Attenuates IL-33-Mediated Mast Cell Function and Peritonitis.
Topics: Adenosine Triphosphate; Animals; Antimetabolites; Cells, Cultured; Deoxyglucose; Disease Models, Ani | 2018 |
Activation of AMPK enhances neutrophil chemotaxis and bacterial killing.
Topics: Actins; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Bacteremia; Chemotaxis, | 2013 |