metformin has been researched along with Postpartum Amenorrhea in 16 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eighty-four women (ages 18-40 years) with first-episode schizophrenia who suffered from amenorrhea during antipsychotic treatment were randomly assigned, in a double-blind study design, to receive 1000 mg/day of metformin or placebo in addition to their antipsychotic treatment for 6 months." | 9.16 | Metformin for treatment of antipsychotic-induced amenorrhea and weight gain in women with first-episode schizophrenia: a double-blind, randomized, placebo-controlled study. ( Chan, PK; Davis, JM; Gao, K; Guo, XF; Jin, H; Ou, JJ; Shao, P; Twamley, EW; Wang, J; Wu, RR; Zhao, JP, 2012) |
| "In 43 amenorrheic women with polycystic ovary syndrome (PCOS), 31 (74%) with fasting hyperinsulinemia (> or =20 microU/mL), our aim was to determine whether Metformin (Bristol-Myers Squibb, Princeton, NJ), which reduces hyperinsulinemia, would reverse the endocrinopathy of PCOS, allowing resumption of regular normal menses." | 9.09 | Metformin-induced resumption of normal menses in 39 of 43 (91%) previously amenorrheic women with the polycystic ovary syndrome. ( Fontaine, R; Glueck, CJ; Sieve-Smith, L; Tracy, T; Wang, P, 1999) |
| "To describe our clinical experience in using Metformin combined with a high protein-low carbohydrate diet to restore normal menstrual cycles in teenaged females with polycystic ovary syndrome (PCOS)." | 9.09 | Metformin to restore normal menses in oligo-amenorrheic teenage girls with polycystic ovary syndrome (PCOS). ( Fontaine, R; Glueck, CJ; Sieve-Smith, L; Tracy, T; Wang, P, 2001) |
| "This study evaluated the use of metformin as first line treatment for patients with polycystic ovary syndrome." | 7.74 | The use of metformin as first line treatment in polycystic ovary syndrome. ( Abbas, M; Gannon, M, 2008) |
| "Eighty-four women (ages 18-40 years) with first-episode schizophrenia who suffered from amenorrhea during antipsychotic treatment were randomly assigned, in a double-blind study design, to receive 1000 mg/day of metformin or placebo in addition to their antipsychotic treatment for 6 months." | 5.16 | Metformin for treatment of antipsychotic-induced amenorrhea and weight gain in women with first-episode schizophrenia: a double-blind, randomized, placebo-controlled study. ( Chan, PK; Davis, JM; Gao, K; Guo, XF; Jin, H; Ou, JJ; Shao, P; Twamley, EW; Wang, J; Wu, RR; Zhao, JP, 2012) |
| "In 43 amenorrheic women with polycystic ovary syndrome (PCOS), 31 (74%) with fasting hyperinsulinemia (> or =20 microU/mL), our aim was to determine whether Metformin (Bristol-Myers Squibb, Princeton, NJ), which reduces hyperinsulinemia, would reverse the endocrinopathy of PCOS, allowing resumption of regular normal menses." | 5.09 | Metformin-induced resumption of normal menses in 39 of 43 (91%) previously amenorrheic women with the polycystic ovary syndrome. ( Fontaine, R; Glueck, CJ; Sieve-Smith, L; Tracy, T; Wang, P, 1999) |
| "To describe our clinical experience in using Metformin combined with a high protein-low carbohydrate diet to restore normal menstrual cycles in teenaged females with polycystic ovary syndrome (PCOS)." | 5.09 | Metformin to restore normal menses in oligo-amenorrheic teenage girls with polycystic ovary syndrome (PCOS). ( Fontaine, R; Glueck, CJ; Sieve-Smith, L; Tracy, T; Wang, P, 2001) |
| "This study evaluated the use of metformin as first line treatment for patients with polycystic ovary syndrome." | 3.74 | The use of metformin as first line treatment in polycystic ovary syndrome. ( Abbas, M; Gannon, M, 2008) |
| "Measures of thrombophilia, hypofibrinolysis, reproductive hormones, and androgenic steroids before and after metformin therapy." | 3.70 | Polycystic ovary syndrome, infertility, familial thrombophilia, familial hypofibrinolysis, recurrent loss of in vitro fertilized embryos, and miscarriage. ( Awadalla, SG; Cameron, D; Fontaine, RN; Glueck, CJ; Phillips, H; Wang, P, 2000) |
| "Polycystic ovary syndrome is recognized as the most common hormonal and metabolic disorder likely to affect women." | 2.52 | [Evidence-based therapy of polycystic ovarian syndrome]. ( Csenteri, OK; Gődény, S, 2015) |
| "Treatment with metformin resulted in progressive improvement of metabolic status, while blood pressure values normalized with atenolol therapy." | 1.40 | LMNA gene mutation as a model of cardiometabolic dysfunction: from genetic analysis to treatment response. ( Amorini, M; Arrigo, T; Briuglia, S; Chirico, V; Ferraù, V; Lacquaniti, A; Loddo, I; Salpietro, C; Salpietro, V, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, P | 1 |
| Liu, X | 1 |
| Gao, J | 1 |
| Qu, S | 1 |
| Zhang, M | 1 |
| Palomba, S | 1 |
| Materazzo, C | 1 |
| Falbo, A | 1 |
| Orio, F | 1 |
| La Sala, GB | 1 |
| Sultan, C | 1 |
| Chirico, V | 1 |
| Ferraù, V | 1 |
| Loddo, I | 1 |
| Briuglia, S | 1 |
| Amorini, M | 1 |
| Salpietro, V | 1 |
| Lacquaniti, A | 1 |
| Salpietro, C | 1 |
| Arrigo, T | 1 |
| Roberts, TK | 1 |
| Fantz, CR | 1 |
| Gődény, S | 1 |
| Csenteri, OK | 1 |
| Li, R | 1 |
| Zhao, J | 1 |
| Wu, R | 1 |
| Langmár, Z | 1 |
| Wu, RR | 1 |
| Jin, H | 1 |
| Gao, K | 1 |
| Twamley, EW | 1 |
| Ou, JJ | 1 |
| Shao, P | 1 |
| Wang, J | 1 |
| Guo, XF | 1 |
| Davis, JM | 1 |
| Chan, PK | 1 |
| Zhao, JP | 1 |
| Smith, RC | 1 |
| Barbieri, RL | 1 |
| Gargiulo, AR | 1 |
| Dronavalli, S | 1 |
| Ehrmann, DA | 1 |
| Genazzani, AD | 1 |
| Lanzoni, C | 1 |
| Ricchieri, F | 1 |
| Baraldi, E | 1 |
| Casarosa, E | 1 |
| Jasonni, VM | 1 |
| Abbas, M | 1 |
| Gannon, M | 1 |
| Glueck, CJ | 3 |
| Wang, P | 3 |
| Fontaine, R | 2 |
| Tracy, T | 2 |
| Sieve-Smith, L | 2 |
| Awadalla, SG | 1 |
| Phillips, H | 1 |
| Cameron, D | 1 |
| Fontaine, RN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| PCOS, Sleep Apnea and Metabolic Risk in Women[NCT00696111] | 80 participants (Anticipated) | Interventional | 2007-12-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for metformin and Postpartum Amenorrhea
| Article | Year |
|---|---|
Metformin, oral contraceptives or both to manage oligo-amenorrhea in adolescents with polycystic ovary syndrome? A clinical review.
Topics: Adolescent; Amenorrhea; Contraceptives, Oral; Female; Humans; Metformin; Polycystic Ovary Syndrome | 2014 |
[Evidence-based therapy of polycystic ovarian syndrome].
Topics: Amenorrhea; Androgen Antagonists; Anovulation; Anti-Obesity Agents; Chorionic Gonadotropin; Contrace | 2015 |
Metformin for the treatment of the polycystic ovary syndrome.
Topics: Adolescent; Adult; Amenorrhea; Clinical Trials as Topic; Clomiphene; Diabetes Mellitus, Type 2; Diab | 2004 |
4 trials available for metformin and Postpartum Amenorrhea
| Article | Year |
|---|---|
Metformin for treatment of antipsychotic-induced amenorrhea and weight gain in women with first-episode schizophrenia: a double-blind, randomized, placebo-controlled study.
Topics: Adolescent; Adult; Amenorrhea; Antipsychotic Agents; Blood Glucose; Body Mass Index; Body Weight; Do | 2012 |
Metformin administration is more effective when non-obese patients with polycystic ovary syndrome show both hyperandrogenism and hyperinsulinemia.
Topics: Adolescent; Adult; Amenorrhea; Female; Glucose Tolerance Test; Humans; Hyperandrogenism; Hyperinsuli | 2007 |
Metformin-induced resumption of normal menses in 39 of 43 (91%) previously amenorrheic women with the polycystic ovary syndrome.
Topics: Adult; Amenorrhea; Blood Glucose; Blood Pressure; Body Mass Index; Female; Hormones; Humans; Hypogly | 1999 |
Metformin to restore normal menses in oligo-amenorrheic teenage girls with polycystic ovary syndrome (PCOS).
Topics: Adolescent; Amenorrhea; Blood Glucose; Case-Control Studies; Cohort Studies; Dietary Carbohydrates; | 2001 |
9 other studies available for metformin and Postpartum Amenorrhea
| Article | Year |
|---|---|
Complete androgen insensitivity syndrome in a young woman with metabolic disorder and diabetes: A case report.
Topics: Amenorrhea; Androgen-Insensitivity Syndrome; Diabetes Mellitus; Dyslipidemias; Female; Humans; Hydro | 2018 |
LMNA gene mutation as a model of cardiometabolic dysfunction: from genetic analysis to treatment response.
Topics: Adolescent; Amenorrhea; Body Fat Distribution; Cardiovascular Diseases; DNA Mutational Analysis; Fem | 2014 |
Easy bruising in a patient with secondary amenorrhea.
Topics: Acne Vulgaris; Adult; Amenorrhea; Contusions; Female; Hormones; Humans; Metformin; Polycystic Ovary | 2014 |
Predictors of menstruation restoration during metformin administration for treatment of antipsychotic drug-induced amenorrhea: A post hoc analysis.
Topics: Amenorrhea; Antipsychotic Agents; Body Weight; Female; Follicle Stimulating Hormone; Humans; Hypogly | 2017 |
[Diagnosis and treatment of polycystic ovary syndrome].
Topics: Acne Vulgaris; Alopecia; Amenorrhea; Androgens; Clomiphene; Diabetes Complications; Diagnosis, Diffe | 2010 |
Metformin as a treatment for antipsychotic drug side effects: special focus on women with schizophrenia.
Topics: Amenorrhea; Antipsychotic Agents; Female; Humans; Hypoglycemic Agents; Metformin; Schizophrenia; Wei | 2012 |
Pharmacologic therapy of polycystic ovary syndrome.
Topics: Amenorrhea; Contraceptives, Oral, Hormonal; Drug Therapy, Combination; Female; Humans; Hyperandrogen | 2007 |
The use of metformin as first line treatment in polycystic ovary syndrome.
Topics: Adolescent; Adult; Amenorrhea; Body Mass Index; Clomiphene; Female; Follicle Stimulating Hormone; Hi | 2008 |
Polycystic ovary syndrome, infertility, familial thrombophilia, familial hypofibrinolysis, recurrent loss of in vitro fertilized embryos, and miscarriage.
Topics: Abortion, Habitual; Adult; Amenorrhea; Androstenedione; Embryo Transfer; Female; Fertilization in Vi | 2000 |