Page last updated: 2024-10-30

metformin and Poisoning

metformin has been researched along with Poisoning in 8 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.

Research Excerpts

ExcerptRelevanceReference
"Metformin-associated lactic acidosis is a well-described and commonly encountered condition associated with significant morbidity and mortality."9.41Expanding the evidence for managing metformin poisoning to support decision-making. ( Ghannoum, M; Roberts, DM, 2023)
"To report a case of severe lactic acidosis and hypoglycemia due to acute metformin intoxication in a dog."7.88Severe lactic acidosis and hypoglycemia due to acute metformin intoxication in a dog. ( Borchers, A; Ueda, Y; Wong, C, 2018)
"Metformin-associated lactic acidosis is a well-described and commonly encountered condition associated with significant morbidity and mortality."5.41Expanding the evidence for managing metformin poisoning to support decision-making. ( Ghannoum, M; Roberts, DM, 2023)
"To report a case of severe lactic acidosis and hypoglycemia due to acute metformin intoxication in a dog."3.88Severe lactic acidosis and hypoglycemia due to acute metformin intoxication in a dog. ( Borchers, A; Ueda, Y; Wong, C, 2018)
" Apart from the traditional indications for renal replacement therapy, there are some cases such as metfomin and ethylene glycol poisoning, lithium intoxication severe hypercalcemia and tumor lysis syndrome, in which intermittent hemodialysis is the most effective treatment, or sometimes the only effective one."3.81[Intermittent hemodialysis, irreplaceable in specific cases of severe poisoning]. ( Burnier, M; Kissling, S; Teta, D; Ventresca, M, 2015)
"Lactic acidosis is a rare and often lethal complication of metformin therapy."3.77Prolonged hemodialysis for severe metformin intoxication. ( Juvvadi, R; McFarren, C; Rifkin, SI; Weinstein, SS, 2011)
"Metformin, widely used in the treatment of diabetes mellitus, is known to cause lactic acidosis in both therapeutic use and after an overdose."3.76Metformin overdose with a resultant serum pH of 6.59: survival without sequalae. ( Algren, DA; Dell'Aglio, DM; Morgan, BW; Perino, LJ; Todino, JD, 2010)
"Poisoning is a common problem in the United States."2.82The Role of the Nephrologist in Management of Poisoning and Intoxication: Core Curriculum 2022. ( Kraut, JA; Mullins, ME, 2022)
"Metformin is an oral hypoglycemic agent used in the management of type 2 diabetes mellitus."1.35Adult metformin ingestions reported to Texas poison control centers, 2000-2006. ( Forrester, MB, 2008)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's4 (50.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Mullins, ME1
Kraut, JA1
Roberts, DM1
Ghannoum, M1
Ueda, Y1
Wong, C1
Borchers, A1
Ventresca, M1
Teta, D1
Burnier, M1
Kissling, S1
Forrester, MB1
Rifkin, SI1
McFarren, C1
Juvvadi, R1
Weinstein, SS1
Panzer, U1
Kluge, S1
Kreymann, G1
Wolf, G1
Dell'Aglio, DM1
Perino, LJ1
Todino, JD1
Algren, DA1
Morgan, BW1

Reviews

2 reviews available for metformin and Poisoning

ArticleYear
The Role of the Nephrologist in Management of Poisoning and Intoxication: Core Curriculum 2022.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2022, Volume: 79, Issue:6

    Topics: Acidosis; Curriculum; Drug Overdose; Humans; Metformin; Nephrologists; Poisoning

2022
Expanding the evidence for managing metformin poisoning to support decision-making.
    Clinical toxicology (Philadelphia, Pa.), 2023, Volume: 61, Issue:4

    Topics: Acidosis; Acidosis, Lactic; Drug Overdose; Humans; Hypoglycemic Agents; Metformin; Poisoning; Renal

2023

Other Studies

6 other studies available for metformin and Poisoning

ArticleYear
Severe lactic acidosis and hypoglycemia due to acute metformin intoxication in a dog.
    Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 2018, Volume: 28, Issue:3

    Topics: Acidosis, Lactic; Animals; Dog Diseases; Dogs; Female; Glucose; Hypoglycemia; Hypoglycemic Agents; I

2018
[Intermittent hemodialysis, irreplaceable in specific cases of severe poisoning].
    Revue medicale suisse, 2015, Feb-25, Volume: 11, Issue:463

    Topics: Ethylene Glycol; Humans; Lithium Compounds; Metformin; Poisoning; Renal Dialysis; Severity of Illnes

2015
Adult metformin ingestions reported to Texas poison control centers, 2000-2006.
    Human & experimental toxicology, 2008, Volume: 27, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Drug Combinations; Female; Humans; Hypoglycemic Agents; Male; Metfor

2008
Prolonged hemodialysis for severe metformin intoxication.
    Renal failure, 2011, Volume: 33, Issue:4

    Topics: Acidosis, Lactic; Acute Kidney Injury; Drug Overdose; Humans; Hypoglycemic Agents; Male; Metformin;

2011
Combination of intermittent haemodialysis and high-volume continuous haemofiltration for the treatment of severe metformin-induced lactic acidosis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:8

    Topics: Acidosis, Lactic; Adult; Hemofiltration; Humans; Hypoglycemic Agents; Male; Metformin; Poisoning; Re

2004
Metformin overdose with a resultant serum pH of 6.59: survival without sequalae.
    The Journal of emergency medicine, 2010, Volume: 39, Issue:1

    Topics: Acidosis, Lactic; Adult; Drug Overdose; Female; Humans; Hypoglycemic Agents; Hypotension; Metformin;

2010