metformin has been researched along with Pneumonia in 6 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Pneumonia: Infection of the lung often accompanied by inflammation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Long-term use of metformin was associated with reduced risk of pneumonia and pneumonia-related death among Chinese individuals with diabetes." | 8.02 | Long-term metformin use and risk of pneumonia and related death in type 2 diabetes: a registry-based cohort study. ( Chan, JCN; Chow, E; Kong, APS; Lau, ESH; Luk, AOY; Ma, RCW; Shi, M; So, WY; Wu, H; Yang, A, 2021) |
| "Long-term use of metformin was associated with reduced risk of pneumonia and pneumonia-related death among Chinese individuals with diabetes." | 4.02 | Long-term metformin use and risk of pneumonia and related death in type 2 diabetes: a registry-based cohort study. ( Chan, JCN; Chow, E; Kong, APS; Lau, ESH; Luk, AOY; Ma, RCW; Shi, M; So, WY; Wu, H; Yang, A, 2021) |
| "Acute respiratory distress syndrome (ARDS), an inflammatory condition with high mortality rates, is common in severe COVID-19, whose risk is reduced by metformin rather than other anti-diabetic medications." | 4.02 | Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation. ( Aleman-Muench, GR; Arditi, M; Chen, W; Crother, TR; de la Torre, JC; Gatchalian, R; Kang, S; Karin, M; Lewis, G; Lipton, SA; Liu, Y; Luevanos, M; Rundberg Nilsson, A; Sanchez-Lopez, E; Soroosh, P; Teijaro, J; Tourtellotte, WG; Trudler, D; Xian, H; Zhang, Y, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 4 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Goto, M | 1 |
| Perencevich, EN | 1 |
| Mohammed, T | 1 |
| Bowe, M | 1 |
| Plant, A | 1 |
| Perez, M | 1 |
| Alvarez, CA | 1 |
| Mortensen, EM | 1 |
| Yang, A | 1 |
| Shi, M | 1 |
| Wu, H | 1 |
| Lau, ESH | 1 |
| Ma, RCW | 1 |
| Kong, APS | 1 |
| So, WY | 1 |
| Luk, AOY | 1 |
| Chan, JCN | 1 |
| Chow, E | 1 |
| Xian, H | 1 |
| Liu, Y | 1 |
| Rundberg Nilsson, A | 1 |
| Gatchalian, R | 1 |
| Crother, TR | 1 |
| Tourtellotte, WG | 1 |
| Zhang, Y | 1 |
| Aleman-Muench, GR | 1 |
| Lewis, G | 1 |
| Chen, W | 1 |
| Kang, S | 1 |
| Luevanos, M | 1 |
| Trudler, D | 1 |
| Lipton, SA | 1 |
| Soroosh, P | 1 |
| Teijaro, J | 1 |
| de la Torre, JC | 1 |
| Arditi, M | 1 |
| Karin, M | 1 |
| Sanchez-Lopez, E | 1 |
| Gorricho, J | 1 |
| Garjón, J | 1 |
| Alonso, A | 1 |
| Celaya, MC | 1 |
| Saiz, LC | 1 |
| Erviti, J | 1 |
| López, A | 1 |
| Myerburg, MM | 1 |
| King, JD | 1 |
| Oyster, NM | 1 |
| Fitch, AC | 1 |
| Magill, A | 1 |
| Baty, CJ | 1 |
| Watkins, SC | 1 |
| Kolls, JK | 1 |
| Pilewski, JM | 1 |
| Hallows, KR | 1 |
6 other studies available for metformin and Pneumonia
| Article | Year |
|---|---|
Metformin and Infections: What Is the Next Step in This Decades-Long Story?
Topics: Diabetes Mellitus; Humans; Hypoglycemic Agents; Metformin; Pneumonia; Veterans | 2023 |
Metformin Use Is Associated With Lower Mortality in Veterans With Diabetes Hospitalized With Pneumonia.
Topics: Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Metformin; Pneumonia; Retrospective Studies; | 2023 |
Long-term metformin use and risk of pneumonia and related death in type 2 diabetes: a registry-based cohort study.
Topics: Acidosis, Lactic; Adult; Asian People; Blood Glucose; China; Cohort Studies; Diabetes Mellitus, Type | 2021 |
Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation.
Topics: Adenosine Triphosphate; Animals; COVID-19; Cytokines; DNA, Mitochondrial; Humans; Inflammasomes; Int | 2021 |
Use of oral antidiabetic agents and risk of community-acquired pneumonia: a nested case-control study.
Topics: Aged; Case-Control Studies; Community-Acquired Infections; Databases, Factual; Diabetes Mellitus, Ty | 2017 |
AMPK agonists ameliorate sodium and fluid transport and inflammation in cystic fibrosis airway epithelial cells.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Anti-Inflammatory Agents; Cell Polarity; | 2010 |