Page last updated: 2024-10-30

metformin and Pneumonia

metformin has been researched along with Pneumonia in 6 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Pneumonia: Infection of the lung often accompanied by inflammation.

Research Excerpts

ExcerptRelevanceReference
"Long-term use of metformin was associated with reduced risk of pneumonia and pneumonia-related death among Chinese individuals with diabetes."8.02Long-term metformin use and risk of pneumonia and related death in type 2 diabetes: a registry-based cohort study. ( Chan, JCN; Chow, E; Kong, APS; Lau, ESH; Luk, AOY; Ma, RCW; Shi, M; So, WY; Wu, H; Yang, A, 2021)
"Long-term use of metformin was associated with reduced risk of pneumonia and pneumonia-related death among Chinese individuals with diabetes."4.02Long-term metformin use and risk of pneumonia and related death in type 2 diabetes: a registry-based cohort study. ( Chan, JCN; Chow, E; Kong, APS; Lau, ESH; Luk, AOY; Ma, RCW; Shi, M; So, WY; Wu, H; Yang, A, 2021)
"Acute respiratory distress syndrome (ARDS), an inflammatory condition with high mortality rates, is common in severe COVID-19, whose risk is reduced by metformin rather than other anti-diabetic medications."4.02Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation. ( Aleman-Muench, GR; Arditi, M; Chen, W; Crother, TR; de la Torre, JC; Gatchalian, R; Kang, S; Karin, M; Lewis, G; Lipton, SA; Liu, Y; Luevanos, M; Rundberg Nilsson, A; Sanchez-Lopez, E; Soroosh, P; Teijaro, J; Tourtellotte, WG; Trudler, D; Xian, H; Zhang, Y, 2021)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's4 (66.67)2.80

Authors

AuthorsStudies
Goto, M1
Perencevich, EN1
Mohammed, T1
Bowe, M1
Plant, A1
Perez, M1
Alvarez, CA1
Mortensen, EM1
Yang, A1
Shi, M1
Wu, H1
Lau, ESH1
Ma, RCW1
Kong, APS1
So, WY1
Luk, AOY1
Chan, JCN1
Chow, E1
Xian, H1
Liu, Y1
Rundberg Nilsson, A1
Gatchalian, R1
Crother, TR1
Tourtellotte, WG1
Zhang, Y1
Aleman-Muench, GR1
Lewis, G1
Chen, W1
Kang, S1
Luevanos, M1
Trudler, D1
Lipton, SA1
Soroosh, P1
Teijaro, J1
de la Torre, JC1
Arditi, M1
Karin, M1
Sanchez-Lopez, E1
Gorricho, J1
Garjón, J1
Alonso, A1
Celaya, MC1
Saiz, LC1
Erviti, J1
López, A1
Myerburg, MM1
King, JD1
Oyster, NM1
Fitch, AC1
Magill, A1
Baty, CJ1
Watkins, SC1
Kolls, JK1
Pilewski, JM1
Hallows, KR1

Other Studies

6 other studies available for metformin and Pneumonia

ArticleYear
Metformin and Infections: What Is the Next Step in This Decades-Long Story?
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023, 04-03, Volume: 76, Issue:7

    Topics: Diabetes Mellitus; Humans; Hypoglycemic Agents; Metformin; Pneumonia; Veterans

2023
Metformin Use Is Associated With Lower Mortality in Veterans With Diabetes Hospitalized With Pneumonia.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023, 04-03, Volume: 76, Issue:7

    Topics: Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Metformin; Pneumonia; Retrospective Studies;

2023
Long-term metformin use and risk of pneumonia and related death in type 2 diabetes: a registry-based cohort study.
    Diabetologia, 2021, Volume: 64, Issue:8

    Topics: Acidosis, Lactic; Adult; Asian People; Blood Glucose; China; Cohort Studies; Diabetes Mellitus, Type

2021
Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation.
    Immunity, 2021, 07-13, Volume: 54, Issue:7

    Topics: Adenosine Triphosphate; Animals; COVID-19; Cytokines; DNA, Mitochondrial; Humans; Inflammasomes; Int

2021
Use of oral antidiabetic agents and risk of community-acquired pneumonia: a nested case-control study.
    British journal of clinical pharmacology, 2017, Volume: 83, Issue:9

    Topics: Aged; Case-Control Studies; Community-Acquired Infections; Databases, Factual; Diabetes Mellitus, Ty

2017
AMPK agonists ameliorate sodium and fluid transport and inflammation in cystic fibrosis airway epithelial cells.
    American journal of respiratory cell and molecular biology, 2010, Volume: 42, Issue:6

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Anti-Inflammatory Agents; Cell Polarity;

2010