metformin has been researched along with Pituitary Diseases in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Pituitary Diseases: Disorders involving either the ADENOHYPOPHYSIS or the NEUROHYPOPHYSIS. These diseases usually manifest as hypersecretion or hyposecretion of PITUITARY HORMONES. Neoplastic pituitary masses can also cause compression of the OPTIC CHIASM and other adjacent structures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin (MET) is a diabetes drug that activates AMP-activated protein kinase (AMPK), and is suggested to have anticancer efficacy." | 1.48 | Metformin inhibits growth and prolactin secretion of pituitary prolactinoma cells and xenografts. ( Bao, X; Deng, K; Feng, M; Gao, J; Han, G; Lian, W; Liu, X; Liu, Y; Lv, X; Wang, R; Xing, B; Yao, Y, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, J | 1 |
| Liu, Y | 1 |
| Han, G | 1 |
| Deng, K | 1 |
| Liu, X | 1 |
| Bao, X | 1 |
| Feng, M | 1 |
| Yao, Y | 1 |
| Lian, W | 1 |
| Xing, B | 1 |
| Lv, X | 1 |
| Wang, R | 1 |
| Mirouze, J | 1 |
| Jaffiol, C | 1 |
| Mary, P | 1 |
2 other studies available for metformin and Pituitary Diseases
| Article | Year |
|---|---|
Metformin inhibits growth and prolactin secretion of pituitary prolactinoma cells and xenografts.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Apoptosis; Bromocriptine; Cell Proliferation; Estroge | 2018 |
[Extragonadal endocrine manifestations of Klinefelter's disease].
Topics: Adrenal Gland Diseases; Adult; Antibodies; Autoantibodies; Blood Glucose; Diabetes Mellitus; Diazoxi | 1973 |