metformin has been researched along with Pigmentary Retinopathy in 5 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin was found to have a neuroprotective effect on the retina in ENU induced rat model of RP." | 5.72 | Can metformin modulate the retinal degenerative changes in a rat model of retinitis pigmentosa? ( Ahmed, AA; Eltony, SA; Mohaseb, HS; Sayed, MM, 2022) |
| "Metformin was found to have a neuroprotective effect on the retina in ENU induced rat model of RP." | 1.72 | Can metformin modulate the retinal degenerative changes in a rat model of retinitis pigmentosa? ( Ahmed, AA; Eltony, SA; Mohaseb, HS; Sayed, MM, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eltony, SA | 1 |
| Mohaseb, HS | 1 |
| Ahmed, AA | 1 |
| Sayed, MM | 1 |
| Nolan, ND | 1 |
| Jenny, LA | 1 |
| Tsang, SH | 1 |
| Cui, X | 1 |
| Brown, EE | 1 |
| Lewin, AS | 1 |
| Ash, JD | 1 |
| Athanasiou, D | 1 |
| Aguila, M | 1 |
| Opefi, CA | 1 |
| South, K | 1 |
| Bellingham, J | 1 |
| Bevilacqua, D | 1 |
| Munro, PM | 1 |
| Kanuga, N | 1 |
| Mackenzie, FE | 1 |
| Dubis, AM | 1 |
| Georgiadis, A | 1 |
| Graca, AB | 1 |
| Pearson, RA | 1 |
| Ali, RR | 1 |
| Sakami, S | 1 |
| Palczewski, K | 1 |
| Sherman, MY | 1 |
| Reeves, PJ | 1 |
| Cheetham, ME | 1 |
| Atabek, ME | 1 |
5 other studies available for metformin and Pigmentary Retinopathy
| Article | Year |
|---|---|
Can metformin modulate the retinal degenerative changes in a rat model of retinitis pigmentosa?
Topics: Animals; Caspase 3; Disease Models, Animal; Humans; Male; Metformin; Rats; Rats, Wistar; Retina; Ret | 2022 |
Rod Photoreceptor-Specific Ablation of Metformin Target, AMPK, in a Preclinical Model of Autosomal Recessive Retinitis Pigmentosa.
Topics: AMP-Activated Protein Kinases; Humans; Metformin; Retina; Retinal Rod Photoreceptor Cells; Retinitis | 2023 |
AMPK May Play an Important Role in the Retinal Metabolic Ecosystem.
Topics: AMP-Activated Protein Kinases; Animals; Disease Models, Animal; DNA Damage; DNA, Mitochondrial; Gene | 2019 |
Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration.
Topics: AMP-Activated Protein Kinases; Animals; Disease Models, Animal; Humans; Metformin; Mice; Mutant Prot | 2017 |
Re: "Effect of metformin and rosiglitazone in a prepubertal boy with Alström syndrome", Sinha SK et al., JPEM 2007; 20: 1045-1052.
Topics: Child; Deafness; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hypoglycemic Agents; | 2008 |