Page last updated: 2024-10-30

metformin and Peritonitis

metformin has been researched along with Peritonitis in 2 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Peritonitis: INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.

Research Excerpts

ExcerptRelevanceReference
" In addition to their effects on chemotaxis, treatment of neutrophils with metformin or aminoimidazole carboxamide ribonucleotide (AICAR) improved phagocytosis and bacterial killing, including more efficient eradication of bacteria in a mouse model of peritonitis-induced sepsis."3.79Activation of AMPK enhances neutrophil chemotaxis and bacterial killing. ( Abraham, E; Deshane, J; Gao, Y; Jiang, S; Park, DW; Stigler, WS; Tadie, JM; Zmijewski, JW, 2013)
"Mast cells are major effectors of allergy and asthma, and can be activated by the alarmin IL-33, which is linked to allergic disease."1.48Inhibiting Glycolysis and ATP Production Attenuates IL-33-Mediated Mast Cell Function and Peritonitis. ( Baldwin, EA; Barnstein, BO; Caslin, HL; Haque, T; Pondicherry, N; Ryan, JJ; Taruselli, MT, 2018)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Caslin, HL1
Taruselli, MT1
Haque, T1
Pondicherry, N1
Baldwin, EA1
Barnstein, BO1
Ryan, JJ1
Park, DW1
Jiang, S1
Tadie, JM1
Stigler, WS1
Gao, Y1
Deshane, J1
Abraham, E1
Zmijewski, JW1

Other Studies

2 other studies available for metformin and Peritonitis

ArticleYear
Inhibiting Glycolysis and ATP Production Attenuates IL-33-Mediated Mast Cell Function and Peritonitis.
    Frontiers in immunology, 2018, Volume: 9

    Topics: Adenosine Triphosphate; Animals; Antimetabolites; Cells, Cultured; Deoxyglucose; Disease Models, Ani

2018
Activation of AMPK enhances neutrophil chemotaxis and bacterial killing.
    Molecular medicine (Cambridge, Mass.), 2013, Nov-08, Volume: 19

    Topics: Actins; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Bacteremia; Chemotaxis,

2013