metformin has been researched along with Periapical Periodontitis in 3 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Periapical Periodontitis: Inflammation of the PERIAPICAL TISSUE. It includes general, unspecified, or acute nonsuppurative inflammation. Chronic nonsuppurative inflammation is PERIAPICAL GRANULOMA. Suppurative inflammation is PERIAPICAL ABSCESS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin was added to the cultures to evaluate its anti-hypoxic effects." | 1.91 | Metformin Reduces Bone Resorption in Apical Periodontitis Through Regulation of Osteoblast and Osteoclast Differentiation. ( Chen, MH; Cheng, SJ; Hong, CY; Kok, SH; Lai, EH; Lin, HY; Lin, SK; Shun, CT; Wang, HW; Wu, FY; Yang, CN; Yang, H, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Hong, CY | 2 |
| Lin, SK | 2 |
| Wang, HW | 2 |
| Shun, CT | 1 |
| Yang, CN | 2 |
| Lai, EH | 2 |
| Cheng, SJ | 1 |
| Chen, MH | 1 |
| Yang, H | 2 |
| Lin, HY | 1 |
| Wu, FY | 1 |
| Kok, SH | 2 |
| Chang, JZ | 1 |
| Liu, L | 1 |
| Zhang, C | 1 |
| Hu, Y | 1 |
| Peng, B | 1 |
3 other studies available for metformin and Periapical Periodontitis
| Article | Year |
|---|---|
Metformin Reduces Bone Resorption in Apical Periodontitis Through Regulation of Osteoblast and Osteoclast Differentiation.
Topics: Animals; Bone Resorption; Cell Differentiation; Core Binding Factor Alpha 1 Subunit; Hypoxia; Metfor | 2023 |
Intracanal Metformin Promotes Healing of Apical Periodontitis via Suppressing Inducible Nitric Oxide Synthase Expression and Monocyte Recruitment.
Topics: Animals; Dental Pulp Cavity; Humans; Lipopolysaccharides; Metformin; Monocytes; Nitric Oxide; Nitric | 2020 |
Protective effect of metformin on periapical lesions in rats by decreasing the ratio of receptor activator of nuclear factor kappa B ligand/osteoprotegerin.
Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents; Bone Remodeling; Injections, Intramuscular; M | 2012 |