Page last updated: 2024-10-30

metformin and Pancreatitis, Chronic

metformin has been researched along with Pancreatitis, Chronic in 5 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Pancreatitis, Chronic: INFLAMMATION of the PANCREAS that is characterized by recurring or persistent ABDOMINAL PAIN with or without STEATORRHEA or DIABETES MELLITUS. It is characterized by the irregular destruction of the pancreatic parenchyma which may be focal, segmental, or diffuse.

Research Excerpts

ExcerptRelevanceReference
"Metformin inhibited pancreatic cancer initiation, suppressed chronic pancreatitis-induced tumorigenesis, and showed promising therapeutic effect in PDAC."3.85Metformin suppresses cancer initiation and progression in genetic mouse models of pancreatic cancer. ( Cao, J; Chen, K; Cheng, L; Duan, W; Gao, L; Jiang, Z; Lei, M; Li, J; Ma, Q; Qian, W; Sun, L; Yan, B; Zhou, C, 2017)
"We explored if known risk factors for pancreatic cancer such as type II diabetes and chronic inflammation, influence the pathophysiology of an established primary tumor in the pancreas and if administration of metformin has an impact on tumor growth."3.81Impact of diabetes type II and chronic inflammation on pancreatic cancer. ( Albert, AC; Amme, J; Bürtin, F; Partecke, LI; Radecke, T; Vollmar, B; Zechner, D, 2015)
"Hepatic insulin resistance is characteristic of T3cDM and is caused by deficiencies of both insulin and pancreatic polypeptide."2.47Pancreatogenic diabetes: special considerations for management. ( Andersen, DK; Cui, Y, 2011)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Dugic, A3
Hagström, H3
Dahlman, I3
Rutkowski, W3
Daou, D3
Kulinski, P3
Löhr, JM3
Vujasinovic, M3
Chen, K1
Qian, W1
Jiang, Z1
Cheng, L1
Li, J1
Sun, L1
Zhou, C1
Gao, L1
Lei, M1
Yan, B1
Cao, J1
Duan, W1
Ma, Q1
Zechner, D1
Radecke, T1
Amme, J1
Bürtin, F1
Albert, AC1
Partecke, LI1
Vollmar, B1
Cui, Y1
Andersen, DK1
Ringel, J1
Lerch, MM1
Mayerle, J1

Reviews

2 reviews available for metformin and Pancreatitis, Chronic

ArticleYear
Pancreatogenic diabetes: special considerations for management.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2011, Volume: 11, Issue:3

    Topics: Administration, Oral; Animals; Diabetes Mellitus; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV In

2011
[Pancreatic diseases: update 2011].
    Deutsche medizinische Wochenschrift (1946), 2011, Volume: 136, Issue:40

    Topics: Antineoplastic Combined Chemotherapy Protocols; Autoimmune Diseases; Diabetes Mellitus; Diagnosis, D

2011

Other Studies

3 other studies available for metformin and Pancreatitis, Chronic

ArticleYear
Post-pancreatitis diabetes mellitus is common in chronic pancreatitis and is associated with adverse outcomes.
    United European gastroenterology journal, 2023, Volume: 11, Issue:1

    Topics: Acute Disease; Cohort Studies; Diabetes Mellitus, Type 2; Female; Humans; Insulins; Male; Metformin;

2023
Post-pancreatitis diabetes mellitus is common in chronic pancreatitis and is associated with adverse outcomes.
    United European gastroenterology journal, 2023, Volume: 11, Issue:1

    Topics: Acute Disease; Cohort Studies; Diabetes Mellitus, Type 2; Female; Humans; Insulins; Male; Metformin;

2023
Post-pancreatitis diabetes mellitus is common in chronic pancreatitis and is associated with adverse outcomes.
    United European gastroenterology journal, 2023, Volume: 11, Issue:1

    Topics: Acute Disease; Cohort Studies; Diabetes Mellitus, Type 2; Female; Humans; Insulins; Male; Metformin;

2023
Post-pancreatitis diabetes mellitus is common in chronic pancreatitis and is associated with adverse outcomes.
    United European gastroenterology journal, 2023, Volume: 11, Issue:1

    Topics: Acute Disease; Cohort Studies; Diabetes Mellitus, Type 2; Female; Humans; Insulins; Male; Metformin;

2023
Metformin suppresses cancer initiation and progression in genetic mouse models of pancreatic cancer.
    Molecular cancer, 2017, 07-24, Volume: 16, Issue:1

    Topics: Animals; Carcinogenesis; Carcinoma in Situ; Carcinoma, Pancreatic Ductal; Disease Models, Animal; Di

2017
Impact of diabetes type II and chronic inflammation on pancreatic cancer.
    BMC cancer, 2015, Feb-13, Volume: 15

    Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Animals; Cell Death; Cell Line, Tumor; Cell

2015