metformin has been researched along with Ototoxicity in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Ototoxicity: Damage to the EAR or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Du, P | 1 |
| Liu, T | 1 |
| Luo, P | 1 |
| Li, H | 1 |
| Tang, W | 1 |
| Zong, S | 1 |
| Xiao, H | 1 |
| Liang, Z | 1 |
| Zhang, T | 1 |
| Zhan, T | 1 |
| Cheng, G | 1 |
| Zhang, W | 1 |
| Jia, H | 1 |
| Yang, H | 1 |
2 other studies available for metformin and Ototoxicity
| Article | Year |
|---|---|
SIRT3/GLUT4 signaling activation by metformin protect against cisplatin-induced ototoxicity in vitro.
Topics: Antineoplastic Agents; Apoptosis; Cisplatin; Humans; Metformin; Ototoxicity; Sirtuin 3 | 2023 |
Metformin alleviates cisplatin-induced ototoxicity by autophagy induction possibly via the AMPK/FOXO3a pathway.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Antineoplastic Agents; Autophagy; Cells, Cultured; Ci | 2021 |