metformin has been researched along with Osteoporosis, Postmenopausal in 5 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Osteoporosis, Postmenopausal: Metabolic disorder associated with fractures of the femoral neck, vertebrae, and distal forearm. It occurs commonly in women within 15-20 years after menopause, and is caused by factors associated with menopause including estrogen deficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the causal relationship between metformin use and osteoporosis and different subtypes of osteoporosis using a 2-sample Mendelian randomization method." | 8.31 | Causal association of metformin and osteoporosis: A 2-sample Mendelian randomization study. ( Chen, PB; Deng, GH; Ju, LL; Wei, YK, 2023) |
| "To investigate the causal relationship between metformin use and osteoporosis and different subtypes of osteoporosis using a 2-sample Mendelian randomization method." | 4.31 | Causal association of metformin and osteoporosis: A 2-sample Mendelian randomization study. ( Chen, PB; Deng, GH; Ju, LL; Wei, YK, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 3 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xie, X | 1 |
| Hu, L | 1 |
| Mi, B | 1 |
| Xue, H | 1 |
| Hu, Y | 1 |
| Panayi, AC | 1 |
| Endo, Y | 1 |
| Chen, L | 1 |
| Yan, C | 1 |
| Lin, Z | 1 |
| Li, H | 1 |
| Zhou, W | 1 |
| Liu, G | 1 |
| Cao, F | 1 |
| Yang, K | 1 |
| Qiu, S | 1 |
| Li, J | 1 |
| Jiang, W | 1 |
| Tao, L | 1 |
| Zhu, Y | 1 |
| Wei, YK | 1 |
| Chen, PB | 1 |
| Ju, LL | 1 |
| Deng, GH | 1 |
| Hegazy, SK | 1 |
| Perry, CG | 1 |
| Connell, JM | 1 |
1 review available for metformin and Osteoporosis, Postmenopausal
| Article | Year |
|---|---|
Key developments in endocrinology.
Topics: Addison Disease; Adjuvants, Immunologic; Dehydroepiandrosterone; Endocrine System Diseases; Female; | 2003 |
1 trial available for metformin and Osteoporosis, Postmenopausal
| Article | Year |
|---|---|
Evaluation of the anti-osteoporotic effects of metformin and sitagliptin in postmenopausal diabetic women.
Topics: Absorptiometry, Photon; Aged; Alkaline Phosphatase; Amino Acids; Bone and Bones; Bone Density; Bone | 2015 |
3 other studies available for metformin and Osteoporosis, Postmenopausal
| Article | Year |
|---|---|
Metformin alleviates bone loss in ovariectomized mice through inhibition of autophagy of osteoclast precursors mediated by E2F1.
Topics: Animals; Autophagy; Bone Resorption; Cell Differentiation; E2F1 Transcription Factor; Female; Humans | 2022 |
Metformin reverses oxidative stress‑induced mitochondrial dysfunction in pre‑osteoblasts via the EGFR/GSK‑3β/calcium pathway.
Topics: Apoptosis; Calcium; ErbB Receptors; Female; Glycogen Synthase Kinase 3 beta; Humans; Metformin; Mito | 2023 |
Causal association of metformin and osteoporosis: A 2-sample Mendelian randomization study.
Topics: Female; Fractures, Spontaneous; Genome-Wide Association Study; Humans; Mendelian Randomization Analy | 2023 |