metformin has been researched along with Neoplasms, Squamous Cell in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Neoplasms, Squamous Cell: Neoplasms of the SQUAMOUS EPITHELIAL CELLS. The concept does not refer to neoplasms located in tissue composed of squamous elements.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A panel of 15 HNSCC cell lines was assayed for glucose and glutamine dependence and sensitivity to metabolic inhibitors." | 5.37 | Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells. ( Davis-Malesevich, M; Fokt, I; Frederick, MJ; Myers, JN; Ow, TJ; Pickering, CR; Priebe, W; Sandulache, VC; Zhou, G, 2011) |
| "Metformin users were more likely to be older, hypertensive, diabetic, and dyslipidemic compared with nonusers (all, P < 0." | 1.46 | Association of Metformin Use and Survival Outcome in Women With Cervical Cancer. ( Brunette, LL; Frimer, M; Hom, MS; Machida, H; Matsuo, K; Mostofizadeh, S; Takiuchi, T, 2017) |
| "A panel of 15 HNSCC cell lines was assayed for glucose and glutamine dependence and sensitivity to metabolic inhibitors." | 1.37 | Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells. ( Davis-Malesevich, M; Fokt, I; Frederick, MJ; Myers, JN; Ow, TJ; Pickering, CR; Priebe, W; Sandulache, VC; Zhou, G, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takiuchi, T | 1 |
| Machida, H | 1 |
| Hom, MS | 1 |
| Mostofizadeh, S | 1 |
| Frimer, M | 1 |
| Brunette, LL | 1 |
| Matsuo, K | 1 |
| Sandulache, VC | 1 |
| Ow, TJ | 1 |
| Pickering, CR | 1 |
| Frederick, MJ | 1 |
| Zhou, G | 1 |
| Fokt, I | 1 |
| Davis-Malesevich, M | 1 |
| Priebe, W | 1 |
| Myers, JN | 1 |
2 other studies available for metformin and Neoplasms, Squamous Cell
| Article | Year |
|---|---|
Association of Metformin Use and Survival Outcome in Women With Cervical Cancer.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Female; Humans; Metformin; Mi | 2017 |
Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells.
Topics: Adenosine Triphosphate; Carcinoma; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Prol | 2011 |