Page last updated: 2024-10-30

metformin and Muscular Diseases

metformin has been researched along with Muscular Diseases in 6 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Muscular Diseases: Acquired, familial, and congenital disorders of SKELETAL MUSCLE and SMOOTH MUSCLE.

Research Excerpts

ExcerptRelevanceReference
" To investigate the effects of metformin on myopathy risks when added to preexisting statin therapy in dyslipidemia patients, we performed a retrospective cohort study using the Korean national health insurance data in statin-treated dyslipidemia patients with or without concomitant metformin use."8.31Impact of metformin on statin-associated myopathy risks in dyslipidemia patients. ( Bak, K; Choi, YJ; Ko, M; Moon, S; Shin, S, 2023)
"A detrimental consequence of hypermethylation is hyperhomocysteinemia (HHcy), that causes oxidative stress, inflammation, and matrix degradation, which leads to multi-pathology in different organs."4.95Hypermethylation: Causes and Consequences in Skeletal Muscle Myopathy. ( Behera, J; Jeremic, N; Majumder, A; Tyagi, SC, 2017)
" To investigate the effects of metformin on myopathy risks when added to preexisting statin therapy in dyslipidemia patients, we performed a retrospective cohort study using the Korean national health insurance data in statin-treated dyslipidemia patients with or without concomitant metformin use."4.31Impact of metformin on statin-associated myopathy risks in dyslipidemia patients. ( Bak, K; Choi, YJ; Ko, M; Moon, S; Shin, S, 2023)
"A 28-year-old Taiwanese woman presented with dyspnoea, poor appetite, and muscle weakness after using antiobesity drugs, including metformin, triiodothyronine, and topiramate."4.02Exacerbation of myopathy triggered by antiobesity drugs in a patient with multiple acyl-CoA dehydrogenase deficiency. ( Liang, WC; Liao, WA; Lin, PY; Sun, YT, 2021)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Bak, K1
Moon, S1
Ko, M1
Choi, YJ1
Shin, S1
Lin, PY1
Liang, WC1
Liao, WA1
Sun, YT1
Paun, DL1
Vija, L1
Stan, E1
Banica, A1
Bobeica, E1
Terzea, D1
Poiana, C1
Badiu, C1
Paun, S1
Majumder, A1
Behera, J1
Jeremic, N1
Tyagi, SC1
Ledl, M1
Hohenecker, J1
Francesconi, C1
Roots, I1
Bauer, MF1
Roden, M1
Duwoos, H1
Bertrand, CM1
Husson, A1
Cramer, J1
Tayot, J1

Reviews

1 review available for metformin and Muscular Diseases

ArticleYear
Hypermethylation: Causes and Consequences in Skeletal Muscle Myopathy.
    Journal of cellular biochemistry, 2017, Volume: 118, Issue:8

    Topics: Animals; DNA Methylation; Epigenesis, Genetic; Folic Acid; Histones; Homocysteine; Humans; Hyperhomo

2017

Other Studies

5 other studies available for metformin and Muscular Diseases

ArticleYear
Impact of metformin on statin-associated myopathy risks in dyslipidemia patients.
    Pharmacology research & perspectives, 2023, Volume: 11, Issue:4

    Topics: Cohort Studies; Dyslipidemias; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic

2023
Exacerbation of myopathy triggered by antiobesity drugs in a patient with multiple acyl-CoA dehydrogenase deficiency.
    BMC neurology, 2021, Feb-27, Volume: 21, Issue:1

    Topics: Adult; Anti-Obesity Agents; Asian People; Carnitine; Female; Humans; Metformin; Multiple Acyl Coenzy

2021
Cushing syndrome secondary to ectopic adrenocorticotropic hormone secretion from a Meckel diverticulum neuroendocrine tumor: case report.
    BMC endocrine disorders, 2015, Nov-26, Volume: 15

    Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Adult; Corticotropin-Releasing Hormone; Cushing

2015
Acute myopathy in a type 2 diabetic patient on combination therapy with metformin, fenofibrate and rosiglitazone.
    Diabetologia, 2005, Volume: 48, Issue:10

    Topics: Aged; Creatine Kinase; Diabetes Mellitus, Type 2; Drug Interactions; Electromyography; Fenofibrate;

2005
[Reversible hyperlactatemia induced by phenformin with muscular asthenia and cardio-respiratory signs].
    La Presse medicale, 1970, Jan-03, Volume: 78, Issue:1

    Topics: Aged; Animals; Asthenia; Diabetes Complications; Diabetic Ketoacidosis; Dyspnea; Heart Diseases; Hep

1970