Page last updated: 2024-10-30

metformin and Muscle Weakness

metformin has been researched along with Muscle Weakness in 5 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Muscle Weakness: A vague complaint of debility, fatigue, or exhaustion attributable to weakness of various muscles. The weakness can be characterized as subacute or chronic, often progressive, and is a manifestation of many muscle and neuromuscular diseases. (From Wyngaarden et al., Cecil Textbook of Medicine, 19th ed, p2251)

Research Excerpts

ExcerptRelevanceReference
"A case of metformin-associated lactic acidosis after elective spinal surgery is reported."7.71Metformin-associated lactic acidosis after elective cervical spine fusion: a case report. ( Brager, MD; Lipsett, PA; Mears, SC; Riley, LH, 2002)
"Metformin is a biguanide antidiabetic drug, with potential to delay aging at cellular and organismal levels."6.82Targeting Myotonic Dystrophy Type 1 with Metformin. ( García-Puga, M; López de Munain, A; Matheu, A; Saenz-Antoñanzas, A, 2022)
"Background: Sepsis is a life-threatening medical emergency, frequently complicated with intensive care unit-acquired weakness syndrome (ICU-AW)."5.91CELLULAR SENESCENCE IMPLICATED IN SEPSIS-INDUCED MUSCLE WEAKNESS AND AMELIORATED WITH METFORMIN. ( Chen, J; Chen, XY; Cong, XX; Huang, M; Sun, YT; Wang, S; Xu, SB; Zheng, LL; Zhou, YT, 2023)
"A 28-year-old Taiwanese woman presented with dyspnoea, poor appetite, and muscle weakness after using antiobesity drugs, including metformin, triiodothyronine, and topiramate."4.02Exacerbation of myopathy triggered by antiobesity drugs in a patient with multiple acyl-CoA dehydrogenase deficiency. ( Liang, WC; Liao, WA; Lin, PY; Sun, YT, 2021)
"A case of metformin-associated lactic acidosis after elective spinal surgery is reported."3.71Metformin-associated lactic acidosis after elective cervical spine fusion: a case report. ( Brager, MD; Lipsett, PA; Mears, SC; Riley, LH, 2002)
"Metformin is a biguanide antidiabetic drug, with potential to delay aging at cellular and organismal levels."2.82Targeting Myotonic Dystrophy Type 1 with Metformin. ( García-Puga, M; López de Munain, A; Matheu, A; Saenz-Antoñanzas, A, 2022)
"Background: Sepsis is a life-threatening medical emergency, frequently complicated with intensive care unit-acquired weakness syndrome (ICU-AW)."1.91CELLULAR SENESCENCE IMPLICATED IN SEPSIS-INDUCED MUSCLE WEAKNESS AND AMELIORATED WITH METFORMIN. ( Chen, J; Chen, XY; Cong, XX; Huang, M; Sun, YT; Wang, S; Xu, SB; Zheng, LL; Zhou, YT, 2023)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's3 (60.00)2.80

Authors

AuthorsStudies
García-Puga, M1
Saenz-Antoñanzas, A1
Matheu, A1
López de Munain, A1
Chen, J1
Chen, XY1
Cong, XX1
Wang, S1
Xu, SB1
Sun, YT2
Zhou, YT1
Zheng, LL1
Huang, M1
Lin, PY1
Liang, WC1
Liao, WA1
Liu, S1
Lee, YF1
Chou, S1
Uno, H1
Li, G1
Brookes, P1
Massett, MP1
Wu, Q1
Chen, LM1
Chang, C1
Mears, SC1
Lipsett, PA1
Brager, MD1
Riley, LH1

Reviews

1 review available for metformin and Muscle Weakness

ArticleYear
Targeting Myotonic Dystrophy Type 1 with Metformin.
    International journal of molecular sciences, 2022, Mar-07, Volume: 23, Issue:5

    Topics: Humans; Hypoglycemic Agents; Metformin; Muscle Weakness; Myotonic Dystrophy; Phenotype

2022

Other Studies

4 other studies available for metformin and Muscle Weakness

ArticleYear
CELLULAR SENESCENCE IMPLICATED IN SEPSIS-INDUCED MUSCLE WEAKNESS AND AMELIORATED WITH METFORMIN.
    Shock (Augusta, Ga.), 2023, 04-01, Volume: 59, Issue:4

    Topics: Animals; Cellular Senescence; Lipopolysaccharides; Metformin; Mice; Muscle Weakness; Sepsis; Tumor S

2023
Exacerbation of myopathy triggered by antiobesity drugs in a patient with multiple acyl-CoA dehydrogenase deficiency.
    BMC neurology, 2021, Feb-27, Volume: 21, Issue:1

    Topics: Adult; Anti-Obesity Agents; Asian People; Carnitine; Female; Humans; Metformin; Multiple Acyl Coenzy

2021
Mice lacking TR4 nuclear receptor develop mitochondrial myopathy with deficiency in complex I.
    Molecular endocrinology (Baltimore, Md.), 2011, Volume: 25, Issue:8

    Topics: Adenosine Triphosphate; Aminoimidazole Carboxamide; Animals; Cells, Cultured; Electron Transport Com

2011
Metformin-associated lactic acidosis after elective cervical spine fusion: a case report.
    Spine, 2002, Nov-15, Volume: 27, Issue:22

    Topics: Acidosis, Lactic; Aged; Aged, 80 and over; Cervical Vertebrae; Humans; Hypoglycemic Agents; Male; Me

2002