metformin has been researched along with Multiple Organ Failure in 7 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Multiple Organ Failure: A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lactic acidosis is a rare but severe complication in patients with type 2 diabetes treated with metformin." | 7.79 | Metformin-induced lactic acidosis associated with multiorganic failure. ( Bajrami, V; Barbullushi, M; Bolleku, E; Idrizi, A; Likaj, E; Nunci, L; Ohri, I; Thereska, N, 2013) |
| "Metformin associated lactic acidosis (MALA) is a rare condition with a prevalence of 3 per 100,000 patient-years." | 7.76 | [Metformin treatment causes persisting lactic acidosis after cardiac arrest]. ( Gamst, J; Hansen, LK; Rasmussen, BS, 2010) |
| " This was due to a severe lactic acidosis caused by acute alcohol intoxication and the use of metformin." | 7.70 | [Severe lactic acidosis due to metformin therapy in a patient with contra-indications for metformin]. ( Holman, ND; Houwerzijl, EJ; Snoek, WJ; van Haastert, M, 2000) |
| "Lactic acidosis is a rare but severe complication in patients with type 2 diabetes treated with metformin." | 3.79 | Metformin-induced lactic acidosis associated with multiorganic failure. ( Bajrami, V; Barbullushi, M; Bolleku, E; Idrizi, A; Likaj, E; Nunci, L; Ohri, I; Thereska, N, 2013) |
| "Metformin associated lactic acidosis (MALA) is a rare condition with a prevalence of 3 per 100,000 patient-years." | 3.76 | [Metformin treatment causes persisting lactic acidosis after cardiac arrest]. ( Gamst, J; Hansen, LK; Rasmussen, BS, 2010) |
| "A 39-year-old woman with type-2 diabetes mellitus presented with metabolic acidosis due to an attempted suicide with metformin." | 3.74 | [Fatal autointoxication with metformin]. ( Bijleveld, YA; de Pont, AC; Franssen, EJ; Hoekstra, JB; Jansen, ME; Kerver, ED, 2007) |
| " This was due to a severe lactic acidosis caused by acute alcohol intoxication and the use of metformin." | 3.70 | [Severe lactic acidosis due to metformin therapy in a patient with contra-indications for metformin]. ( Holman, ND; Houwerzijl, EJ; Snoek, WJ; van Haastert, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bolleku, E | 1 |
| Idrizi, A | 1 |
| Barbullushi, M | 1 |
| Bajrami, V | 1 |
| Likaj, E | 1 |
| Thereska, N | 1 |
| Ohri, I | 1 |
| Nunci, L | 1 |
| Gamst, J | 1 |
| Hansen, LK | 1 |
| Rasmussen, BS | 1 |
| Williams, FN | 1 |
| Branski, LK | 1 |
| Jeschke, MG | 1 |
| Herndon, DN | 1 |
| Mustafa, E | 1 |
| Lai, L | 1 |
| Lien, YH | 1 |
| de Pont, AC | 1 |
| Kerver, ED | 1 |
| Jansen, ME | 1 |
| Bijleveld, YA | 1 |
| Franssen, EJ | 1 |
| Hoekstra, JB | 1 |
| Aquarius, M | 1 |
| van Kuijk, WH | 1 |
| Houwerzijl, EJ | 1 |
| Snoek, WJ | 1 |
| van Haastert, M | 1 |
| Holman, ND | 1 |
1 review available for metformin and Multiple Organ Failure
| Article | Year |
|---|---|
What, how, and how much should patients with burns be fed?
Topics: Animals; Blood Glucose; Burns; Catecholamines; Enteral Nutrition; Humans; Hypoglycemic Agents; Insul | 2011 |
6 other studies available for metformin and Multiple Organ Failure
| Article | Year |
|---|---|
Metformin-induced lactic acidosis associated with multiorganic failure.
Topics: Acidosis, Lactic; Adult; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Metformin; | 2013 |
[Metformin treatment causes persisting lactic acidosis after cardiac arrest].
Topics: Acidosis, Lactic; Cardiopulmonary Resuscitation; Diabetes Mellitus, Type 2; Fatal Outcome; Heart Arr | 2010 |
Rapid recovery from acute kidney injury in a patient with metformin-associated lactic acidosis and hypothermia.
Topics: Acidosis, Lactic; Acute Kidney Injury; Anti-Bacterial Agents; Comorbidity; Female; Humans; Hypotherm | 2012 |
[Fatal autointoxication with metformin].
Topics: Acidosis; Adult; Diabetes Mellitus, Type 2; Drug Overdose; Fatal Outcome; Female; Humans; Hypoglycem | 2007 |
[Fatal autointoxication with metformin].
Topics: Acidosis; Female; Humans; Hypoglycemic Agents; Metformin; Multiple Organ Failure | 2007 |
[Severe lactic acidosis due to metformin therapy in a patient with contra-indications for metformin].
Topics: Acidosis, Lactic; Alcoholic Intoxication; Contraindications; Diabetes Mellitus, Type 2; Fatal Outcom | 2000 |