metformin has been researched along with Lymph Node Metastasis in 5 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "While overall there was no statistically significant association between metformin exposure and disseminated colorectal cancer at diagnosis, there was a suggestion that high intensity, exclusive metformin use may be associated with reduced odds of disseminated disease." | 7.80 | Metformin exposure and disseminated disease in patients with colorectal cancer. ( Barron, TI; Bennett, K; Sharp, L; Spillane, S, 2014) |
| "While overall there was no statistically significant association between metformin exposure and disseminated colorectal cancer at diagnosis, there was a suggestion that high intensity, exclusive metformin use may be associated with reduced odds of disseminated disease." | 3.80 | Metformin exposure and disseminated disease in patients with colorectal cancer. ( Barron, TI; Bennett, K; Sharp, L; Spillane, S, 2014) |
| "The occurrence of colorectal cancer (CRC) is associated with a variety of oncogenes and tumor‑suppressor genes." | 1.51 | Molecular mechanism of LKB1 in the invasion and metastasis of colorectal cancer. ( Chen, Y; Liu, Y; You, H; Zhou, Y, 2019) |
| "Metformin use was identified in 456 patients (13." | 1.43 | Metformin Use Is Associated with Improved Survival in Patients Undergoing Resection for Pancreatic Cancer. ( Canner, J; Cerullo, M; Chen, SY; Gani, F; Pawlik, TM, 2016) |
| "Metformin treatment leaded to increased expression of pACC, which, in turn, resulted in the reduction of cell proliferation and colony formation of gastric cancer cells (P < 0." | 1.40 | Increased expression of phospho-acetyl-CoA carboxylase protein is an independent prognostic factor for human gastric cancer without lymph node metastasis. ( Chen, Y; Cui, H; Fang, W; Wang, J; Yu, D; Yu, G, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y | 2 |
| Liu, Y | 1 |
| Zhou, Y | 1 |
| You, H | 1 |
| Rieken, M | 1 |
| Xylinas, E | 1 |
| Kluth, L | 1 |
| Trinh, QD | 1 |
| Lee, RK | 1 |
| Fajkovic, H | 1 |
| Novara, G | 1 |
| Margulis, V | 1 |
| Lotan, Y | 1 |
| Martinez-Salamanca, JI | 1 |
| Matsumoto, K | 1 |
| Seitz, C | 1 |
| Remzi, M | 1 |
| Karakiewicz, PI | 1 |
| Scherr, DS | 1 |
| Briganti, A | 1 |
| Kautzky-Willer, A | 1 |
| Bachmann, A | 1 |
| Shariat, SF | 1 |
| Spillane, S | 1 |
| Bennett, K | 1 |
| Sharp, L | 1 |
| Barron, TI | 1 |
| Fang, W | 1 |
| Cui, H | 1 |
| Yu, D | 1 |
| Wang, J | 1 |
| Yu, G | 1 |
| Cerullo, M | 1 |
| Gani, F | 1 |
| Chen, SY | 1 |
| Canner, J | 1 |
| Pawlik, TM | 1 |
5 other studies available for metformin and Lymph Node Metastasis
| Article | Year |
|---|---|
Molecular mechanism of LKB1 in the invasion and metastasis of colorectal cancer.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Cell Line, Tumor; Cell Prolifer | 2019 |
Diabetes mellitus without metformin intake is associated with worse oncologic outcomes after radical nephroureterectomy for upper tract urothelial carcinoma.
Topics: Aged; Carcinoma, Transitional Cell; Diabetes Mellitus; Female; Follow-Up Studies; Humans; Hypoglycem | 2014 |
Metformin exposure and disseminated disease in patients with colorectal cancer.
Topics: Aged; Aged, 80 and over; Colorectal Neoplasms; Databases, Factual; Dose-Response Relationship, Drug; | 2014 |
Increased expression of phospho-acetyl-CoA carboxylase protein is an independent prognostic factor for human gastric cancer without lymph node metastasis.
Topics: Acetyl-CoA Carboxylase; Aged; Biomarkers, Tumor; Cell Proliferation; Female; Humans; Kaplan-Meier Es | 2014 |
Metformin Use Is Associated with Improved Survival in Patients Undergoing Resection for Pancreatic Cancer.
Topics: Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Lymphatic Metastasis; Male; Metformin; Middl | 2016 |