metformin has been researched along with Learning Disabilities in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Learning Disabilities: Conditions characterized by a significant discrepancy between an individual's perceived level of intellect and their ability to acquire new language and other cognitive skills. These may result from organic or psychological conditions. Relatively common subtypes include DYSLEXIA, DYSCALCULIA, and DYSGRAPHIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The mice fed with HFD were dosed with metformin (200 mg/kg) or thymol (20, 40 mg/kg) daily." | 5.46 | Thymol improves high-fat diet-induced cognitive deficits in mice via ameliorating brain insulin resistance and upregulating NRF2/HO-1 pathway. ( Li, H; Li, M; Ma, S; Qin, T, 2017) |
| "Metformin was injected intraperitoneally in dose of 200mg/kg along with alternate-day PTZ." | 5.40 | Metformin protects against seizures, learning and memory impairments and oxidative damage induced by pentylenetetrazole-induced kindling in mice. ( Liu, LM; Wang, WP; Xu, F; Xu, XC; Zhang, WL; Zhao, RR, 2014) |
| " The mice fed with HFD were dosed with metformin (200 mg/kg) or thymol (20, 40 mg/kg) daily." | 1.46 | Thymol improves high-fat diet-induced cognitive deficits in mice via ameliorating brain insulin resistance and upregulating NRF2/HO-1 pathway. ( Li, H; Li, M; Ma, S; Qin, T, 2017) |
| "Metformin was injected intraperitoneally in dose of 200mg/kg along with alternate-day PTZ." | 1.40 | Metformin protects against seizures, learning and memory impairments and oxidative damage induced by pentylenetetrazole-induced kindling in mice. ( Liu, LM; Wang, WP; Xu, F; Xu, XC; Zhang, WL; Zhao, RR, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, RR | 1 |
| Xu, XC | 1 |
| Xu, F | 1 |
| Zhang, WL | 2 |
| Liu, LM | 1 |
| Wang, WP | 1 |
| Li, H | 1 |
| Qin, T | 1 |
| Li, M | 1 |
| Ma, S | 1 |
2 other studies available for metformin and Learning Disabilities
| Article | Year |
|---|---|
Metformin protects against seizures, learning and memory impairments and oxidative damage induced by pentylenetetrazole-induced kindling in mice.
Topics: Animals; Antioxidants; Brain; Convulsants; Glutathione; Kindling, Neurologic; Learning Disabilities; | 2014 |
Thymol improves high-fat diet-induced cognitive deficits in mice via ameliorating brain insulin resistance and upregulating NRF2/HO-1 pathway.
Topics: Animals; Antioxidants; Cognition Disorders; Cytokines; Diet, High-Fat; Heme Oxygenase-1; Hypoglycemi | 2017 |