metformin has been researched along with Kidney Stones in 3 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In rats with nephrolithiasis, MH treatment significantly rescued the down-regulation of the mRNA and protein expression of Nrf2 and HO-1 in the kidneys." | 1.91 | Metformin ameliorates calcium oxalate crystallization and stone formation by activating the Nrf2/HO-1 signaling pathway: Two birds with one stone. ( Jiang, Y; Li, T; Liang, F; Ren, F; Zhang, X, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, X | 2 |
| Liang, F | 1 |
| Li, T | 1 |
| Jiang, Y | 1 |
| Ren, F | 1 |
| Yang, X | 2 |
| Yang, T | 2 |
| Li, J | 2 |
| Yang, R | 1 |
| Qi, S | 2 |
| Zhao, Y | 1 |
| Li, L | 1 |
| Yang, K | 2 |
| Xu, Y | 2 |
| Liu, C | 2 |
| Ding, H | 1 |
| Qin, Z | 1 |
| Zhang, C | 1 |
| Zhang, H | 1 |
| He, Z | 1 |
| Du, E | 1 |
| Zhang, Z | 1 |
3 other studies available for metformin and Kidney Stones
| Article | Year |
|---|---|
Metformin ameliorates calcium oxalate crystallization and stone formation by activating the Nrf2/HO-1 signaling pathway: Two birds with one stone.
Topics: Animals; Calcium Oxalate; Crystallization; Kidney; Kidney Calculi; Metformin; NF-E2-Related Factor 2 | 2023 |
Metformin prevents nephrolithiasis formation by inhibiting the expression of OPN and MCP-1 in vitro and in vivo.
Topics: Animals; Body Weight; Cell Death; Chemokine CCL2; Disease Models, Animal; Dogs; Ethylene Glycol; Hum | 2019 |
Metformin Prevents Renal Stone Formation through an Antioxidant Mechanism In Vitro and In Vivo.
Topics: Animals; Antioxidants; Cell Death; Disease Models, Animal; Dogs; Ethylene Glycol; Humans; Kidney Cal | 2016 |