metformin has been researched along with Intracranial Aneurysm in 1 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Intracranial Aneurysm: Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin is a 5' AMP-activated protein kinase (AMPK) agonist that has a protective effect on vasculature." | 5.56 | Metformin inhibits intracranial aneurysm formation and progression by regulating vascular smooth muscle cell phenotype switching via the AMPK/ACC pathway. ( Fan, Z; Li, S; Liu, P; Liu, Y; Quan, K; Shi, Y; Song, Y; Ying, L; Yu, G; Zhu, W, 2020) |
| "Metformin is a 5' AMP-activated protein kinase (AMPK) agonist that has a protective effect on vasculature." | 1.56 | Metformin inhibits intracranial aneurysm formation and progression by regulating vascular smooth muscle cell phenotype switching via the AMPK/ACC pathway. ( Fan, Z; Li, S; Liu, P; Liu, Y; Quan, K; Shi, Y; Song, Y; Ying, L; Yu, G; Zhu, W, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, S | 1 |
| Shi, Y | 1 |
| Liu, P | 1 |
| Song, Y | 1 |
| Liu, Y | 1 |
| Ying, L | 1 |
| Quan, K | 1 |
| Yu, G | 1 |
| Fan, Z | 1 |
| Zhu, W | 1 |
1 other study available for metformin and Intracranial Aneurysm
| Article | Year |
|---|---|
Metformin inhibits intracranial aneurysm formation and progression by regulating vascular smooth muscle cell phenotype switching via the AMPK/ACC pathway.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Disease Progression; Intracranial An | 2020 |