metformin has been researched along with Intervertebral Disc Displacement in 3 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Intervertebral Disc Displacement: An INTERVERTEBRAL DISC in which the NUCLEUS PULPOSUS has protruded through surrounding ANNULUS FIBROSUS. This occurs most frequently in the lower lumbar region.
| Excerpt | Relevance | Reference |
|---|---|---|
| "LDH evoked persistent thermal hyperalgesia and mechanical allodynia on the ipsilateral paw, as indicated by the decreased PWL and 50% PWT." | 1.51 | AMP-Activated Protein Kinase Activation in Dorsal Root Ganglion Suppresses mTOR/p70S6K Signaling and Alleviates Painful Radiculopathies in Lumbar Disc Herniation Rat Model. ( Guo, Y; Li, H; Li, J; Li, Z; Liu, Y; Liu, Z; Shang, Y, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Li, JX | 1 |
| Hsu, TJ | 1 |
| Hsu, SB | 1 |
| Lin, YH | 1 |
| Liu, Y | 1 |
| Li, J | 1 |
| Li, H | 1 |
| Shang, Y | 1 |
| Guo, Y | 1 |
| Li, Z | 1 |
| Liu, Z | 1 |
| Tokmak, M | 1 |
| Altiok, IB | 1 |
| Guven, M | 1 |
| Aras, AB | 1 |
| Cosar, M | 1 |
3 other studies available for metformin and Intervertebral Disc Displacement
| Article | Year |
|---|---|
Strong association of lumbar disk herniation with diabetes mellitus: a 12-year nationwide retrospective cohort study.
Topics: Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Intervertebral Disc Displacement; Male; Metf | 2023 |
AMP-Activated Protein Kinase Activation in Dorsal Root Ganglion Suppresses mTOR/p70S6K Signaling and Alleviates Painful Radiculopathies in Lumbar Disc Herniation Rat Model.
Topics: AMP-Activated Protein Kinases; Animals; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Inter | 2019 |
Spontaneous Regression of Lumbar Disc Herniation After Weight Loss: Case Report.
Topics: Adult; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Intervertebral Disc Displacem | 2015 |