metformin has been researched along with Infections, Staphylococcal in 3 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin used for the treatment of diabetes increases transepithelial resistance (TEER) and partially prevents the effect of bacteria but the mechanisms of action are unclear." | 1.51 | Metformin attenuates the effect of Staphylococcus aureus on airway tight junctions by increasing PKCĪ¶-mediated phosphorylation of occludin. ( Baines, DL; Baker, EH; Dockrell, ME; Garnett, JP; Kalsi, KK; Patkee, W; Weekes, A, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Abdel-Karim, SAM | 1 |
| El-Ganiny, AMA | 1 |
| El-Sayed, MA | 1 |
| Abbas, HAA | 1 |
| Kalsi, KK | 1 |
| Garnett, JP | 1 |
| Patkee, W | 1 |
| Weekes, A | 1 |
| Dockrell, ME | 1 |
| Baker, EH | 1 |
| Baines, DL | 1 |
| Colapinto, P | 1 |
| Aslam, SA | 1 |
| Frangouli, O | 1 |
| Joshi, N | 1 |
3 other studies available for metformin and Infections, Staphylococcal
| Article | Year |
|---|---|
Promising FDA-approved drugs with efflux pump inhibitory activities against clinical isolates of Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Diclofenac; Domperidone; Humans; Metformin; Microbial Sen | 2022 |
Metformin attenuates the effect of Staphylococcus aureus on airway tight junctions by increasing PKCĪ¶-mediated phosphorylation of occludin.
Topics: Cell Line; Claudin-1; Epithelial Cells; Host-Pathogen Interactions; Humans; Metformin; Occludin; Pho | 2019 |
Undiagnosed type 2 diabetes mellitus presenting with orbital cellulitis.
Topics: Anti-Bacterial Agents; Combined Modality Therapy; Decompression, Surgical; Diabetes Mellitus, Type 2 | 2008 |