metformin has been researched along with Infections, Plasmodium in 5 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin has well known anti-malarial properties." | 2.55 | Malaria and diabetes. ( Aggarwal, S; Dutta, D; Kalra, S; Khandelwal, D; Singla, R, 2017) |
| "KRas is frequently mutated in pancreatic cancers." | 1.62 | GSK-3β Can Regulate the Sensitivity of MIA-PaCa-2 Pancreatic and MCF-7 Breast Cancer Cells to Chemotherapeutic Drugs, Targeted Therapeutics and Nutraceuticals. ( Abrams, SL; Akula, SM; Candido, S; Cervello, M; Cocco, L; Duda, P; Falzone, L; Gizak, A; Libra, M; Martelli, AM; McCubrey, JA; Meher, AK; Montalto, G; Rakus, D; Ratti, S; Ruvolo, P; Steelman, LS, 2021) |
| "Pretreatment with metformin for 21 days followed by infection with P." | 1.51 | Plasmodium Infection Induces Dyslipidemia and a Hepatic Lipogenic State in the Host through the Inhibition of the AMPK-ACC Pathway. ( Araujo, MFC; Atella, GC; Atella, TC; da Rocha, I; Imperio, GED; Kluck, GEG; Miranda, KR; Wendt, CHC, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kluck, GEG | 1 |
| Wendt, CHC | 1 |
| Imperio, GED | 1 |
| Araujo, MFC | 1 |
| Atella, TC | 1 |
| da Rocha, I | 1 |
| Miranda, KR | 1 |
| Atella, GC | 1 |
| Vera, IM | 1 |
| Grilo Ruivo, MT | 1 |
| Lemos Rocha, LF | 1 |
| Marques, S | 1 |
| Bhatia, SN | 1 |
| Mota, MM | 1 |
| Mancio-Silva, L | 1 |
| Abrams, SL | 1 |
| Akula, SM | 1 |
| Meher, AK | 1 |
| Steelman, LS | 1 |
| Gizak, A | 1 |
| Duda, P | 1 |
| Rakus, D | 1 |
| Martelli, AM | 1 |
| Ratti, S | 1 |
| Cocco, L | 1 |
| Montalto, G | 1 |
| Cervello, M | 1 |
| Ruvolo, P | 1 |
| Libra, M | 1 |
| Falzone, L | 1 |
| Candido, S | 1 |
| McCubrey, JA | 1 |
| Kalra, S | 1 |
| Khandelwal, D | 1 |
| Singla, R | 1 |
| Aggarwal, S | 1 |
| Dutta, D | 1 |
| Miyakoda, M | 1 |
| Bayarsaikhan, G | 1 |
| Kimura, D | 1 |
| Akbari, M | 1 |
| Udono, H | 1 |
| Yui, K | 1 |
1 review available for metformin and Infections, Plasmodium
| Article | Year |
|---|---|
Malaria and diabetes.
Topics: Animals; Antimalarials; Diabetes Mellitus, Type 2; Female; Glucosephosphate Dehydrogenase Deficiency | 2017 |
4 other studies available for metformin and Infections, Plasmodium
| Article | Year |
|---|---|
Plasmodium Infection Induces Dyslipidemia and a Hepatic Lipogenic State in the Host through the Inhibition of the AMPK-ACC Pathway.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Cholesterol; Dyslipidemias; Fatty Ac | 2019 |
Targeting liver stage malaria with metformin.
Topics: Animals; Antimalarials; Cells, Cultured; Disease Models, Animal; Drug Evaluation, Preclinical; Drug | 2019 |
GSK-3β Can Regulate the Sensitivity of MIA-PaCa-2 Pancreatic and MCF-7 Breast Cancer Cells to Chemotherapeutic Drugs, Targeted Therapeutics and Nutraceuticals.
Topics: Adenocarcinoma; Adenylate Kinase; Antineoplastic Agents; bcl-X Protein; Berberine; Biphenyl Compound | 2021 |
Metformin Promotes the Protection of Mice Infected With
Topics: Animals; Disease Models, Animal; Female; Humans; Lymphocyte Activation; Malaria; Metformin; Mice; Mi | 2018 |