metformin has been researched along with Hypotension, Orthostatic in 1 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Hypotension, Orthostatic: A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin treatment did not affect VDT group difference - 0." | 2.94 | Metformin may adversely affect orthostatic blood pressure recovery in patients with type 2 diabetes: substudy from the placebo-controlled Copenhagen Insulin and Metformin Therapy (CIMT) trial. ( Almdal, T; Carstensen, B; Gluud, C; Hansen, CS; Hedetoft, C; Hemmingsen, B; Jørgensen, ME; Krarup, T; Lund, SS; Lundby-Christiansen, L; Madsbad, S; Sneppen, SB; Tarnow, L; Thorsteinsson, B; Wiinberg, N, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hansen, CS | 1 |
| Lundby-Christiansen, L | 1 |
| Tarnow, L | 1 |
| Gluud, C | 1 |
| Hedetoft, C | 1 |
| Thorsteinsson, B | 1 |
| Hemmingsen, B | 1 |
| Wiinberg, N | 1 |
| Sneppen, SB | 1 |
| Lund, SS | 1 |
| Krarup, T | 1 |
| Madsbad, S | 1 |
| Almdal, T | 1 |
| Carstensen, B | 1 |
| Jørgensen, ME | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Metformin Versus Placebo, Including Three Insulin-Analogue Regimens With Variating Postprandial Glucose Regulation, on CIMT in T2DM Patients - A Randomized, Multicenter Trial[NCT00657943] | Phase 4 | 415 participants (Actual) | Interventional | 2008-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for metformin and Hypotension, Orthostatic
| Article | Year |
|---|---|
Metformin may adversely affect orthostatic blood pressure recovery in patients with type 2 diabetes: substudy from the placebo-controlled Copenhagen Insulin and Metformin Therapy (CIMT) trial.
Topics: Aged; Autonomic Nervous System Diseases; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Neuropa | 2020 |