metformin has been researched along with Hypopharyngeal Neoplasms in 3 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Hypopharyngeal Neoplasms: Tumors or cancer of the HYPOPHARYNX.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin is proven to improve the prognosis of various cancers, but it is unknown if metformin could ameliorate hypopharyngeal cancer in diabetes mellitus patients." | 3.91 | The effect of metformin use on hypopharyngeal squamous cell carcinoma in diabetes mellitus patients. ( Chang, WD; Chen, CM; Chen, HL; Lu, JJ; Tsai, MH; Tsou, YA; Wu, TF, 2019) |
| "Metformin may inhibit the proliferation of Fadu cells by inducing the cell cycle arrest in G1 phase mediated in part by AMPK and P21." | 1.40 | [Metformin inhibits the proliferation of hypopharyngeal carcinoma Fadu cells and enhances the chemotherapeutic sensitivity of cells]. ( Li, X; Lu, X; Zhang, M, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsou, YA | 1 |
| Chang, WD | 1 |
| Lu, JJ | 1 |
| Wu, TF | 1 |
| Chen, HL | 1 |
| Chen, CM | 1 |
| Tsai, MH | 1 |
| Zhang, M | 1 |
| Li, X | 1 |
| Lu, X | 1 |
| Sun, R | 1 |
| Ma, X | 1 |
| Cai, X | 1 |
| Pan, X | 1 |
| Liu, D | 1 |
3 other studies available for metformin and Hypopharyngeal Neoplasms
| Article | Year |
|---|---|
The effect of metformin use on hypopharyngeal squamous cell carcinoma in diabetes mellitus patients.
Topics: Aged; Carcinoma, Squamous Cell; Case-Control Studies; Chemoradiotherapy; Diabetes Mellitus, Type 2; | 2019 |
[Metformin inhibits the proliferation of hypopharyngeal carcinoma Fadu cells and enhances the chemotherapeutic sensitivity of cells].
Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, | 2014 |
The effect and mechanism of action of metformin on in vitro FaDu cell proliferation.
Topics: Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Proliferation; Humans; Hypoglycemic Agents; Hy | 2016 |