metformin has been researched along with Hypertension, Pregnancy-Induced in 10 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Hypertension, Pregnancy-Induced: A condition in pregnant women with elevated systolic (
| Excerpt | Relevance | Reference |
|---|---|---|
| "gov for randomized controlled trials (RCTs) that compared metformin to insulin in pregnancy." | 9.22 | The efficacy and safety of metformin alone or as an add-on therapy to insulin in pregnancy with GDM or T2DM: A systematic review and meta-analysis of 21 randomized controlled trials. ( Ge, J; Guo, Q; He, K; Jing, Z; Li, C; Li, J, 2022) |
| "To prospectively evaluate the safety of metformin administration during pregnancy in a group of PCOS patients by assessing its effect on the prevalence of gestational complications and neonatal outcome." | 9.15 | The administration of metformin during pregnancy reduces polycystic ovary syndrome related gestational complications. ( De Leo, V; Di Sabatino, A; Morgante, G; Musacchio, MC; Piomboni, P, 2011) |
| " 'Cases' were women with PCOS who conceived while taking Metformin and it whom it was continued throughout pregnancy." | 9.14 | Continuation of metformin reduces early pregnancy loss in obese Pakistani women with polycystic ovarian syndrome. ( Nawaz, FH; Rizvi, J, 2010) |
| "Metformin has been reported to reduce the risk of pre-eclampsia." | 8.98 | Metformin for prevention of hypertensive disorders of pregnancy in women with gestational diabetes or obesity: systematic review and meta-analysis of randomized trials. ( Abdi, A; Kalafat, E; Khalil, A; Sukur, YE; Thilaganathan, B, 2018) |
| "This article is a review of the literature assessing pregnancy outcomes and the effect of metformin treatment among women with polycystic ovary syndrome (PCOS)." | 8.88 | Pregnancy outcomes and the effect of metformin treatment in women with polycystic ovary syndrome: an overview. ( Awwad, JT; Ghazeeri, GS; Nassar, AH; Younes, Z, 2012) |
| " We compared patients who received metformin throughout pregnancy to those with no metformin exposure." | 8.02 | Metformin Exposure and Risk of Hypertensive Disorders of Pregnancy in Patients with Type 2 Diabetes. ( Adams, JH; Antony, KM; Eddy, A; Hoppe, KK; Iruretagoyena, JI; Racine, JL; Rhoades, JS; Stewart, KS, 2021) |
| "gov for randomized controlled trials (RCTs) that compared metformin to insulin in pregnancy." | 5.22 | The efficacy and safety of metformin alone or as an add-on therapy to insulin in pregnancy with GDM or T2DM: A systematic review and meta-analysis of 21 randomized controlled trials. ( Ge, J; Guo, Q; He, K; Jing, Z; Li, C; Li, J, 2022) |
| "To prospectively evaluate the safety of metformin administration during pregnancy in a group of PCOS patients by assessing its effect on the prevalence of gestational complications and neonatal outcome." | 5.15 | The administration of metformin during pregnancy reduces polycystic ovary syndrome related gestational complications. ( De Leo, V; Di Sabatino, A; Morgante, G; Musacchio, MC; Piomboni, P, 2011) |
| " 'Cases' were women with PCOS who conceived while taking Metformin and it whom it was continued throughout pregnancy." | 5.14 | Continuation of metformin reduces early pregnancy loss in obese Pakistani women with polycystic ovarian syndrome. ( Nawaz, FH; Rizvi, J, 2010) |
| "Metformin has been reported to reduce the risk of pre-eclampsia." | 4.98 | Metformin for prevention of hypertensive disorders of pregnancy in women with gestational diabetes or obesity: systematic review and meta-analysis of randomized trials. ( Abdi, A; Kalafat, E; Khalil, A; Sukur, YE; Thilaganathan, B, 2018) |
| "This article is a review of the literature assessing pregnancy outcomes and the effect of metformin treatment among women with polycystic ovary syndrome (PCOS)." | 4.88 | Pregnancy outcomes and the effect of metformin treatment in women with polycystic ovary syndrome: an overview. ( Awwad, JT; Ghazeeri, GS; Nassar, AH; Younes, Z, 2012) |
| " We compared patients who received metformin throughout pregnancy to those with no metformin exposure." | 4.02 | Metformin Exposure and Risk of Hypertensive Disorders of Pregnancy in Patients with Type 2 Diabetes. ( Adams, JH; Antony, KM; Eddy, A; Hoppe, KK; Iruretagoyena, JI; Racine, JL; Rhoades, JS; Stewart, KS, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 3 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carris, NW | 1 |
| Nwabuobi, CK | 1 |
| He, W | 1 |
| Bullers, K | 1 |
| Wilson, RE | 1 |
| Louis, JM | 1 |
| Magness, RR | 1 |
| Racine, JL | 1 |
| Adams, JH | 1 |
| Antony, KM | 1 |
| Hoppe, KK | 1 |
| Iruretagoyena, JI | 1 |
| Stewart, KS | 1 |
| Eddy, A | 1 |
| Rhoades, JS | 1 |
| He, K | 1 |
| Guo, Q | 1 |
| Ge, J | 1 |
| Li, J | 1 |
| Li, C | 1 |
| Jing, Z | 1 |
| Soobryan, N | 1 |
| Murugesan, S | 1 |
| Pandiyan, A | 1 |
| Moodley, J | 1 |
| Mackraj, I | 1 |
| Kalafat, E | 1 |
| Sukur, YE | 1 |
| Abdi, A | 1 |
| Thilaganathan, B | 1 |
| Khalil, A | 1 |
| Zhao, LP | 1 |
| Sheng, XY | 1 |
| Zhou, S | 1 |
| Yang, T | 1 |
| Ma, LY | 1 |
| Zhou, Y | 1 |
| Cui, YM | 1 |
| Nawaz, FH | 1 |
| Rizvi, J | 1 |
| De Leo, V | 1 |
| Musacchio, MC | 1 |
| Piomboni, P | 1 |
| Di Sabatino, A | 1 |
| Morgante, G | 1 |
| Ghazeeri, GS | 1 |
| Nassar, AH | 1 |
| Younes, Z | 1 |
| Awwad, JT | 1 |
| Homburg, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prevention of Pre-eclampsia Using Metformin: a Randomized Control Trial[NCT04855513] | 414 participants (Anticipated) | Interventional | 2022-03-24 | Not yet recruiting | |||
| Preventing Recurrent Gestational Diabetes Mellitus With Early Metformin Intervention[NCT02394158] | Phase 4 | 112 participants (Anticipated) | Interventional | 2015-01-27 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for metformin and Hypertension, Pregnancy-Induced
| Article | Year |
|---|---|
Review of Prediabetes and Hypertensive Disorders of Pregnancy.
Topics: Blood Glucose Self-Monitoring; Diet Therapy; Exercise; Female; Glycated Hemoglobin; Humans; Hyperten | 2021 |
The efficacy and safety of metformin alone or as an add-on therapy to insulin in pregnancy with GDM or T2DM: A systematic review and meta-analysis of 21 randomized controlled trials.
Topics: Birth Weight; Diabetes Mellitus, Type 2; Diabetes, Gestational; Drug Therapy, Combination; Female; G | 2022 |
Angiogenic Dysregulation in Pregnancy-Related Hypertension-A Role for Metformin.
Topics: Angiogenesis Inducing Agents; Animals; Endothelial Cells; Female; Humans; Hypertension, Pregnancy-In | 2018 |
Metformin for prevention of hypertensive disorders of pregnancy in women with gestational diabetes or obesity: systematic review and meta-analysis of randomized trials.
Topics: Bayes Theorem; Diabetes, Gestational; Female; Glyburide; Humans; Hypertension, Pregnancy-Induced; In | 2018 |
Metformin versus insulin for gestational diabetes mellitus: a meta-analysis.
Topics: Diabetes, Gestational; Female; Humans; Hypertension, Pregnancy-Induced; Insulin; Metformin; Pregnanc | 2015 |
Pregnancy outcomes and the effect of metformin treatment in women with polycystic ovary syndrome: an overview.
Topics: Abortion, Spontaneous; Diabetes, Gestational; Female; Humans; Hyperandrogenism; Hyperinsulinism; Hyp | 2012 |
Pregnancy complications in PCOS.
Topics: Abortion, Spontaneous; Diabetes, Gestational; Female; Humans; Hyperinsulinism; Hypertension, Pregnan | 2006 |
2 trials available for metformin and Hypertension, Pregnancy-Induced
| Article | Year |
|---|---|
Continuation of metformin reduces early pregnancy loss in obese Pakistani women with polycystic ovarian syndrome.
Topics: Abortion, Habitual; Adult; Body Mass Index; Case-Control Studies; Diabetes, Gestational; Female; Fet | 2010 |
The administration of metformin during pregnancy reduces polycystic ovary syndrome related gestational complications.
Topics: Abortion, Spontaneous; Adult; Blood Glucose; Diabetes, Gestational; Female; Humans; Hyperinsulinism; | 2011 |
The administration of metformin during pregnancy reduces polycystic ovary syndrome related gestational complications.
Topics: Abortion, Spontaneous; Adult; Blood Glucose; Diabetes, Gestational; Female; Humans; Hyperinsulinism; | 2011 |
The administration of metformin during pregnancy reduces polycystic ovary syndrome related gestational complications.
Topics: Abortion, Spontaneous; Adult; Blood Glucose; Diabetes, Gestational; Female; Humans; Hyperinsulinism; | 2011 |
The administration of metformin during pregnancy reduces polycystic ovary syndrome related gestational complications.
Topics: Abortion, Spontaneous; Adult; Blood Glucose; Diabetes, Gestational; Female; Humans; Hyperinsulinism; | 2011 |
1 other study available for metformin and Hypertension, Pregnancy-Induced
| Article | Year |
|---|---|
Metformin Exposure and Risk of Hypertensive Disorders of Pregnancy in Patients with Type 2 Diabetes.
Topics: Adult; Birth Weight; Diabetes Mellitus, Type 2; Female; Fetal Growth Retardation; Humans; Hypertensi | 2021 |