metformin has been researched along with Hyperprolactinaemia in 16 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The study included two age-, weight-, lipid-, and prolactin level-matched groups of premenopausal women with hypecholesterolemia and a history of hyperprolactinemia: patients treated with bromocriptine (5." | 9.20 | The Effect of Atorvastatin on Cardiometabolic Risk Factors in Bromocriptine-Treated Premenopausal Women with Isolated Hypercholesterolemia. ( Gilowski, W; Krysiak, R; Okopien, B; Szkrobka, W, 2015) |
| " This meta-analysis of randomized controlled trials systematically examined the efficacy and safety of adjunctive metformin for antipsychotic-related hyperprolactinemia in schizophrenia patients." | 8.95 | Adjunctive metformin for antipsychotic-related hyperprolactinemia: A meta-analysis of randomized controlled trials. ( Cai, DB; Ng, CH; Ning, YP; Ungvari, GS; Wang, N; Xiang, YT; Yang, XH; Zheng, W, 2017) |
| "This systematic review examines adjunctive metformin therapy for the treatment of antipsychotic-induced hyperprolactinemia." | 8.93 | Adjunctive metformin for antipsychotic-induced hyperprolactinemia: A systematic review. ( Bo, QJ; de Leon, J; Li, XB; Ma, X; Wang, CY; Wang, ZM, 2016) |
| "Metformin reduced prolactin levels only in women with hyperprolactinemia." | 8.02 | The Impact of Ethinyl Estradiol on Metformin Action on Prolactin Levels in Women with Hyperprolactinemia. ( Krysiak, R; Okopień, B; Szkróbka, W, 2021) |
| "The study included 20 women with antipsychotic-induced hyperprolactinemia and 12 normoprolactinemic women, who, because of coexisting glucose metabolism abnormalities, were treated for 6months with metformin." | 7.83 | The effect of metformin on prolactin levels in patients with drug-induced hyperprolactinemia. ( Kowalcze, K; Krysiak, R; Okopien, B; Szkrobka, W, 2016) |
| " This study was aimed at investigating whether metformin treatment has an impact on plasma prolactin levels in bromocriptine-treated patients with hyperprolactinaemia and impaired glucose tolerance." | 7.81 | The effect of short-term metformin treatment on plasma prolactin levels in bromocriptine-treated patients with hyperprolactinaemia and impaired glucose tolerance: a pilot study. ( Krysiak, R; Okopien, B; Okrzesik, J, 2015) |
| "The study included two age-, weight-, lipid-, and prolactin level-matched groups of premenopausal women with hypecholesterolemia and a history of hyperprolactinemia: patients treated with bromocriptine (5." | 5.20 | The Effect of Atorvastatin on Cardiometabolic Risk Factors in Bromocriptine-Treated Premenopausal Women with Isolated Hypercholesterolemia. ( Gilowski, W; Krysiak, R; Okopien, B; Szkrobka, W, 2015) |
| " This meta-analysis of randomized controlled trials systematically examined the efficacy and safety of adjunctive metformin for antipsychotic-related hyperprolactinemia in schizophrenia patients." | 4.95 | Adjunctive metformin for antipsychotic-related hyperprolactinemia: A meta-analysis of randomized controlled trials. ( Cai, DB; Ng, CH; Ning, YP; Ungvari, GS; Wang, N; Xiang, YT; Yang, XH; Zheng, W, 2017) |
| "This systematic review examines adjunctive metformin therapy for the treatment of antipsychotic-induced hyperprolactinemia." | 4.93 | Adjunctive metformin for antipsychotic-induced hyperprolactinemia: A systematic review. ( Bo, QJ; de Leon, J; Li, XB; Ma, X; Wang, CY; Wang, ZM, 2016) |
| "The obtained results suggest that myo-inositol supplementation potentiates the inhibitory effect of metformin on prolactin levels in women with hyperprolactinemia." | 4.31 | Myo-Inositol Potentiates the Inhibitory Effect of Metformin on Prolactin Levels. ( Basiak, M; Krysiak, R; Okopień, B; Szkróbka, W, 2023) |
| " Ten adult patients (26-61 years) with prolactinomas (7 M), persistent hyperprolactinemia (38-386 ng/mL) under cabergoline treatment (2-7 mg/week) for at least 6 months (6-108 months), features of metabolic syndrome, and not taking metformin were included." | 4.12 | Prolactin Response to Metformin in Cabergoline-Resistant Prolactinomas: A Pilot Study. ( Abucham, J; Correa-Silva, SR; Portari, LHC, 2022) |
| " Because of coexistent prediabetes, all individuals received metformin (2." | 4.02 | The impact of metformin on prolactin levels in postmenopausal women. ( Kowalcze, K; Krysiak, R; Okopień, B, 2021) |
| "Metformin reduced prolactin levels only in women with hyperprolactinemia." | 4.02 | The Impact of Ethinyl Estradiol on Metformin Action on Prolactin Levels in Women with Hyperprolactinemia. ( Krysiak, R; Okopień, B; Szkróbka, W, 2021) |
| "The study included 20 women with antipsychotic-induced hyperprolactinemia and 12 normoprolactinemic women, who, because of coexisting glucose metabolism abnormalities, were treated for 6months with metformin." | 3.83 | The effect of metformin on prolactin levels in patients with drug-induced hyperprolactinemia. ( Kowalcze, K; Krysiak, R; Okopien, B; Szkrobka, W, 2016) |
| " This study was aimed at investigating whether metformin treatment has an impact on plasma prolactin levels in bromocriptine-treated patients with hyperprolactinaemia and impaired glucose tolerance." | 3.81 | The effect of short-term metformin treatment on plasma prolactin levels in bromocriptine-treated patients with hyperprolactinaemia and impaired glucose tolerance: a pilot study. ( Krysiak, R; Okopien, B; Okrzesik, J, 2015) |
| "Metformin was found to reduce circulating levels of pituitary hormones." | 2.87 | Sex-Dependent Effect of Metformin on Serum Prolactin Levels In Hyperprolactinemic Patients With Type 2 Diabetes: A Pilot Study. ( Krysiak, R; Okopień, B; Szkróbka, W, 2018) |
| "Hypogonadotropic anovulation is treated with exogenous gonadotropins, and little has changed in its management." | 2.43 | Ovulatory disorders and infertility. ( Urman, B; Yakin, K, 2006) |
| "Metformin was found to normalize secretory function of overactive pituitary cells." | 1.62 | Vitamin D status determines the impact of metformin on circulating prolactin levels in premenopausal women. ( Kowalcze, K; Krysiak, R; Okopień, B, 2021) |
| "Metformin was found to reduce elevated prolactin levels in women but not in men." | 1.56 | Endogenous testosterone determines metformin action on prolactin levels in hyperprolactinaemic men: A pilot study. ( Krysiak, R; Okopień, B; Szkróbka, W, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 8 (50.00) | 24.3611 |
| 2020's | 6 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Krysiak, R | 10 |
| Basiak, M | 1 |
| Szkróbka, W | 7 |
| Okopień, B | 10 |
| Portari, LHC | 1 |
| Correa-Silva, SR | 1 |
| Abucham, J | 1 |
| Kowalcze, K | 3 |
| Zheng, W | 1 |
| Yang, XH | 1 |
| Cai, DB | 1 |
| Ungvari, GS | 1 |
| Ng, CH | 1 |
| Wang, N | 1 |
| Ning, YP | 1 |
| Xiang, YT | 1 |
| Ke, RW | 1 |
| Okrzesik, J | 1 |
| Gilowski, W | 1 |
| Bo, QJ | 1 |
| Wang, ZM | 1 |
| Li, XB | 1 |
| Ma, X | 1 |
| Wang, CY | 1 |
| de Leon, J | 1 |
| Urman, B | 1 |
| Yakin, K | 1 |
| Check, JH | 1 |
4 reviews available for metformin and Hyperprolactinaemia
| Article | Year |
|---|---|
Adjunctive metformin for antipsychotic-related hyperprolactinemia: A meta-analysis of randomized controlled trials.
Topics: Adolescent; Adult; Antipsychotic Agents; Female; Humans; Hyperprolactinemia; Male; Metformin; Middle | 2017 |
Endocrine basis for recurrent pregnancy loss.
Topics: Abortion, Habitual; Female; Humans; Hyperinsulinism; Hyperprolactinemia; Hypoglycemic Agents; Lutein | 2014 |
Adjunctive metformin for antipsychotic-induced hyperprolactinemia: A systematic review.
Topics: Antipsychotic Agents; Clinical Trials as Topic; Female; Humans; Hyperprolactinemia; Hypoglycemic Age | 2016 |
Ovulatory disorders and infertility.
Topics: Anovulation; Clomiphene; Female; Fertility Agents, Female; Glucocorticoids; Gonadotropin-Releasing H | 2006 |
2 trials available for metformin and Hyperprolactinaemia
| Article | Year |
|---|---|
Sex-Dependent Effect of Metformin on Serum Prolactin Levels In Hyperprolactinemic Patients With Type 2 Diabetes: A Pilot Study.
Topics: Adolescent; Adult; Diabetes Mellitus, Type 2; Female; Humans; Hyperprolactinemia; Lactotrophs; Male; | 2018 |
The Effect of Atorvastatin on Cardiometabolic Risk Factors in Bromocriptine-Treated Premenopausal Women with Isolated Hypercholesterolemia.
Topics: Adult; Atorvastatin; Bromocriptine; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, LDL; D | 2015 |
10 other studies available for metformin and Hyperprolactinaemia
| Article | Year |
|---|---|
Myo-Inositol Potentiates the Inhibitory Effect of Metformin on Prolactin Levels.
Topics: Adrenocorticotropic Hormone; Blood Glucose; Female; Glycated Hemoglobin; Humans; Hyperprolactinemia; | 2023 |
Endogenous testosterone determines metformin action on prolactin levels in hyperprolactinaemic men: A pilot study.
Topics: Adult; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 2; Humans; Hyperprolactinemia; H | 2020 |
Prolactin Response to Metformin in Cabergoline-Resistant Prolactinomas: A Pilot Study.
Topics: Adult; Cabergoline; Dopamine Agonists; Drug Resistance; Drug Therapy, Combination; Female; Humans; H | 2022 |
Vitamin D status determines the impact of metformin on circulating prolactin levels in premenopausal women.
Topics: Adult; Blood Glucose; Body Mass Index; Comorbidity; Female; Gonadal Steroid Hormones; Humans; Hyperp | 2021 |
The impact of metformin on prolactin levels in postmenopausal women.
Topics: Aged; Blood Glucose; Body Mass Index; Comorbidity; Estradiol; Estrogen Replacement Therapy; Female; | 2021 |
The Impact of Ethinyl Estradiol on Metformin Action on Prolactin Levels in Women with Hyperprolactinemia.
Topics: Adult; Blood Glucose; Case-Control Studies; Contraceptives, Oral, Hormonal; Diabetes Mellitus; Ethin | 2021 |
The effect of short-term metformin treatment on plasma prolactin levels in bromocriptine-treated patients with hyperprolactinaemia and impaired glucose tolerance: a pilot study.
Topics: Adult; Bromocriptine; Dopamine Agonists; Female; Glucose Intolerance; Humans; Hyperprolactinemia; Hy | 2015 |
The effect of metformin on prolactin levels in patients with drug-induced hyperprolactinemia.
Topics: Adult; Antipsychotic Agents; Blood Glucose; Diabetes Mellitus, Type 2; Female; Humans; Hyperprolacti | 2016 |
A Neutral Effect of Metformin Treatment on Macroprolactin Content in Women with Macroprolactinemia.
Topics: Adult; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Humans; Hyperprolactinemia; Metformi | 2017 |
Ovulation disorders: Part II. Anovulation associated with normal estrogen.
Topics: Adrenal Hyperplasia, Congenital; Anovulation; Cervix Mucus; Clomiphene; Drug Therapy, Combination; E | 2007 |