metformin has been researched along with Hormone-Dependent Neoplasms in 7 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Breast cancer is the most common cancer in women worldwide." | 2.52 | Update on breast cancer risk prediction and prevention. ( Cuzick, J; Sestak, I, 2015) |
| "Obesity is associated with a range of health outcomes that are of clinical and public health significance, including cancer." | 2.52 | Obesity and cancer: mechanistic insights from transdisciplinary studies. ( Allott, EH; Hursting, SD, 2015) |
| "Cases of endometrial cancer have increased in recent years, but the prognosis of patients with this disease has also been improved by combined modality therapy with surgery, radiotherapy and chemotherapy." | 2.49 | New candidate therapeutic agents for endometrial cancer: potential for clinical practice (review). ( Aoki, D; Banno, K; Kisu, I; Kobayashi, Y; Masuda, K; Nogami, Y; Susumu, N; Tominaga, E; Tsuji, K; Ueki, A; Umene, K; Yamagami, W; Yanokura, M, 2013) |
| "Endometrial carcinoma is the common malignant tumor of the female genital tract, and its incidence is increasing." | 2.48 | Endometrial carcinoma tumorigenesis and pharmacotherapy research. ( Fang, S; Huang, H; Shu, J; Teichman, PG; Xing, L, 2012) |
| "Metformin was found to reduce androgen-dependent cell growth and the expression of AR target genes by inhibiting AR function in prostate cancer cells such as LNCaP and C4-2 cells." | 1.40 | SMILE upregulated by metformin inhibits the function of androgen receptor in prostate cancer cells. ( Choi, HS; Jung, C; Lee, K; Lee, SY; Song, CH; Xie, YB, 2014) |
| "Metformin use lead to lower MBD in 4 of 14 (28." | 1.38 | [The influence of metformin and N-acetylcysteine on mammographic density in postmenopausal women]. ( Bershteĭn, LM; Boiarkina, MP; Kisel'nikov, KS; Kovalenko, IG; Poroshina, TE; Vasil'ev, DA; Zaĭtsev, AN, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, SY | 1 |
| Song, CH | 1 |
| Xie, YB | 1 |
| Jung, C | 1 |
| Choi, HS | 1 |
| Lee, K | 1 |
| Sestak, I | 1 |
| Cuzick, J | 1 |
| Allott, EH | 1 |
| Hursting, SD | 1 |
| Bershteĭn, LM | 2 |
| Semiglazov, VF | 1 |
| Vasil'ev, DA | 1 |
| Kovalenko, IG | 1 |
| Poroshina, TE | 1 |
| Kisel'nikov, KS | 1 |
| Boiarkina, MP | 1 |
| Zaĭtsev, AN | 1 |
| Shu, J | 1 |
| Fang, S | 1 |
| Teichman, PG | 1 |
| Xing, L | 1 |
| Huang, H | 1 |
| Umene, K | 1 |
| Banno, K | 1 |
| Kisu, I | 1 |
| Yanokura, M | 1 |
| Nogami, Y | 1 |
| Tsuji, K | 1 |
| Masuda, K | 1 |
| Ueki, A | 1 |
| Kobayashi, Y | 1 |
| Yamagami, W | 1 |
| Tominaga, E | 1 |
| Susumu, N | 1 |
| Aoki, D | 1 |
5 reviews available for metformin and Hormone-Dependent Neoplasms
| Article | Year |
|---|---|
Update on breast cancer risk prediction and prevention.
Topics: Age of Onset; Aromatase Inhibitors; Aspirin; Biomarkers, Tumor; Breast Neoplasms; Diphosphonates; Fe | 2015 |
Obesity and cancer: mechanistic insights from transdisciplinary studies.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Breast Neoplasms; Caloric R | 2015 |
[Breast cancer subtypes and their endocrine-metabolic basis; practical aspects].
Topics: Age Factors; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; BRCA1 Protein; Breast Neoplasms; Fe | 2011 |
Endometrial carcinoma tumorigenesis and pharmacotherapy research.
Topics: Adenocarcinoma, Clear Cell; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Carcinoma, Endom | 2012 |
New candidate therapeutic agents for endometrial cancer: potential for clinical practice (review).
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Endometrial Neoplasms; Fe | 2013 |
2 other studies available for metformin and Hormone-Dependent Neoplasms
| Article | Year |
|---|---|
SMILE upregulated by metformin inhibits the function of androgen receptor in prostate cancer cells.
Topics: Animals; Basic-Leucine Zipper Transcription Factors; Cell Growth Processes; Cell Line, Tumor; HEK293 | 2014 |
[The influence of metformin and N-acetylcysteine on mammographic density in postmenopausal women].
Topics: Acetylcysteine; Aged; Apoptosis; Breast; Breast Neoplasms; Cell Proliferation; DNA Repair; Female; H | 2012 |