metformin has been researched along with Hepatolenticular Degeneration in 1 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Hepatolenticular Degeneration: A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. It is caused by defects in the ATP7B gene encoding copper-transporting ATPase 2 (EC 3.6.3.4), also known as the Wilson disease protein. The overload of copper inevitably leads to progressive liver and neurological dysfunction such as LIVER CIRRHOSIS; TREMOR; ATAXIA and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 1 |
| Jiang, Y | 1 |
| Xu, T | 1 |
| Zhang, Y | 1 |
| Xue, J | 1 |
| Gao, X | 1 |
| Yang, X | 1 |
| Wang, X | 1 |
| Jia, X | 1 |
| Cheng, W | 1 |
| Jin, S | 1 |
1 other study available for metformin and Hepatolenticular Degeneration
| Article | Year |
|---|---|
Wilson Disease With Novel Compound Heterozygote Mutations in the
Topics: Chelating Agents; Chelation Therapy; China; Copper; Copper-Transporting ATPases; Diabetes Mellitus; | 2020 |