metformin has been researched along with Hemorrhagic Shock in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin treatment ameliorated organ injury and mean arterial blood pressure in both WT and KO mice, without affecting systemic cytokine levels." | 5.48 | Metformin Exerts Beneficial Effects in Hemorrhagic Shock in An AMPKα1-Independent Manner. ( Hake, PW; Kim, P; Lahni, P; O'Connor, M; Piraino, G; Wolfe, V; Zingarelli, B, 2018) |
| "Treatment with metformin improved cardiovascular function and survival in mature animals of both genders." | 5.46 | Metformin ameliorates gender-and age-dependent hemodynamic instability and myocardial injury in murine hemorrhagic shock. ( Hake, PW; James, J; Lahni, P; Matsiukevich, D; O'Connor, M; Piraino, G; Wolfe, V; Zingarelli, B, 2017) |
| "Treatment with metformin improved cardiovascular function and survival in mature animals of both genders." | 1.46 | Metformin ameliorates gender-and age-dependent hemodynamic instability and myocardial injury in murine hemorrhagic shock. ( Hake, PW; James, J; Lahni, P; Matsiukevich, D; O'Connor, M; Piraino, G; Wolfe, V; Zingarelli, B, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matsiukevich, D | 1 |
| Piraino, G | 2 |
| Lahni, P | 2 |
| Hake, PW | 2 |
| Wolfe, V | 2 |
| O'Connor, M | 2 |
| James, J | 1 |
| Zingarelli, B | 2 |
| Kim, P | 1 |
2 other studies available for metformin and Hemorrhagic Shock
| Article | Year |
|---|---|
Metformin ameliorates gender-and age-dependent hemodynamic instability and myocardial injury in murine hemorrhagic shock.
Topics: Aging; AMP-Activated Protein Kinases; Animals; Biomarkers; Cardiotonic Agents; Enzyme Activators; Fe | 2017 |
Metformin Exerts Beneficial Effects in Hemorrhagic Shock in An AMPKα1-Independent Manner.
Topics: AMP-Activated Protein Kinases; Animals; Electron Transport Complex II; Metformin; Mice; Mice, Knocko | 2018 |