metformin has been researched along with Hamartoma Syndrome, Multiple in 1 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Hamartoma Syndrome, Multiple: A hereditary disease characterized by multiple ectodermal, mesodermal, and endodermal nevoid and neoplastic anomalies. Facial trichilemmomas and papillomatous papules of the oral mucosa are the most characteristic lesions. Individuals with this syndrome have a high risk of BREAST CANCER; THYROID CANCER; and ENDOMETRIAL CANCER. This syndrome is associated with mutations in the gene for PTEN PHOSPHATASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin promotes a proinflammatory phenotype by blocking anti-inflammatory cytokine response, whereas rapamycin reduces production of proinflammatory cytokines." | 1.51 | Effect of PTEN inactivating germline mutations on innate immune cell function and thyroid cancer-induced macrophages in patients with PTEN hamartoma tumor syndrome. ( Hoogerbrugge, N; Netea, MG; Netea-Maier, RT; Rabold, K; Sloot, YJE; Smit, JWA, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sloot, YJE | 1 |
| Rabold, K | 1 |
| Netea, MG | 1 |
| Smit, JWA | 1 |
| Hoogerbrugge, N | 1 |
| Netea-Maier, RT | 1 |
1 other study available for metformin and Hamartoma Syndrome, Multiple
| Article | Year |
|---|---|
Effect of PTEN inactivating germline mutations on innate immune cell function and thyroid cancer-induced macrophages in patients with PTEN hamartoma tumor syndrome.
Topics: Adult; beta-Glucans; Case-Control Studies; Cell Line, Tumor; Coculture Techniques; Cytokines; Germ-L | 2019 |