metformin has been researched along with Graves Ophthalmopathy in 4 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Graves Ophthalmopathy: An autoimmune disorder of the EYE, occurring in patients with Graves disease. Subtypes include congestive (inflammation of the orbital connective tissue), myopathic (swelling and dysfunction of the extraocular muscles), and mixed congestive-myopathic ophthalmopathy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "As metformin has multiple therapeutic effects in many autoimmune diseases, we explored the effects of metformin on TAO in an in vitro fibroblast model." | 5.72 | Metformin Attenuates Inflammation and Fibrosis in Thyroid-Associated Ophthalmopathy. ( Sha, X; Sun, A; Xiao, W; Xu, Z; Yang, H; Yang, S; Ye, H; Zhang, T, 2022) |
| "As metformin has multiple therapeutic effects in many autoimmune diseases, we explored the effects of metformin on TAO in an in vitro fibroblast model." | 1.72 | Metformin Attenuates Inflammation and Fibrosis in Thyroid-Associated Ophthalmopathy. ( Sha, X; Sun, A; Xiao, W; Xu, Z; Yang, H; Yang, S; Ye, H; Zhang, T, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, Z | 1 |
| Ye, H | 1 |
| Xiao, W | 1 |
| Sun, A | 1 |
| Yang, S | 1 |
| Zhang, T | 1 |
| Sha, X | 1 |
| Yang, H | 1 |
| Han, YE | 1 |
| Hwang, S | 1 |
| Kim, JH | 1 |
| Byun, JW | 1 |
| Yoon, JS | 1 |
| Lee, EJ | 1 |
| Koch, CA | 1 |
| Krabbe, S | 1 |
| Hehmke, B | 1 |
| Lee, S | 1 |
| Tsirbas, A | 1 |
| Goldberg, RA | 1 |
| McCann, JD | 1 |
1 review available for metformin and Graves Ophthalmopathy
| Article | Year |
|---|---|
Statins, metformin, proprotein-convertase-subtilisin-kexin type-9 (PCSK9) inhibitors and sex hormones: Immunomodulatory properties?
Topics: Gonadal Steroid Hormones; Graves Ophthalmopathy; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibit | 2018 |
3 other studies available for metformin and Graves Ophthalmopathy
| Article | Year |
|---|---|
Metformin Attenuates Inflammation and Fibrosis in Thyroid-Associated Ophthalmopathy.
Topics: AMP-Activated Protein Kinases; Fibrosis; Graves Ophthalmopathy; Humans; Inflammation; Metformin | 2022 |
Biguanides Metformin and Phenformin Generate Therapeutic Effects via AMP-Activated Protein Kinase/Extracellular-Regulated Kinase Pathways in an In Vitro Model of Graves' Orbitopathy.
Topics: Adipocytes; Adipogenesis; AMP-Activated Protein Kinases; Fibroblasts; Graves Ophthalmopathy; Humans; | 2018 |
Thiazolidinedione induced thyroid associated orbitopathy.
Topics: Diplopia; Disease Progression; Drug Therapy, Combination; Exophthalmos; Female; Graves Ophthalmopath | 2007 |