metformin has been researched along with Graves Disease in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Graves Disease: A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of the study was to describe the clinical and biochemical findings of four patients with chronic hypothyroidism, previously euthyroid on fixed doses of L-T4 for several years, in whom the metformin was initiated." | 3.73 | Thyrotropin suppression by metformin. ( Filmore-Nassar, A; Glass, AR; Vigersky, RA, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vigersky, RA | 1 |
| Filmore-Nassar, A | 1 |
| Glass, AR | 1 |
| Watts, NB | 1 |
| Blevins, LS | 1 |
2 other studies available for metformin and Graves Disease
| Article | Year |
|---|---|
Thyrotropin suppression by metformin.
Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Interactions; Female; Goiter; Graves D | 2006 |
Endocrinology.
Topics: Bone Resorption; Endocrinology; Graves Disease; Humans; Hyperparathyroidism; Hypoglycemic Agents; Me | 1996 |