metformin has been researched along with Goiter in 3 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Goiter: Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency (HYPOTHYROIDISM), or hormone overproduction (HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic (GOITER, ENDEMIC).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We demonstrate an inhibitory effect of metformin on prevalent and incident goiter." | 3.79 | Metformin inhibits goitrogenous effects of type 2 diabetes. ( Derwahl, M; Ittermann, T; Markus, MR; Meisinger, C; Schipf, S; Völzke, H, 2013) |
| "The objective of the study was to describe the clinical and biochemical findings of four patients with chronic hypothyroidism, previously euthyroid on fixed doses of L-T4 for several years, in whom the metformin was initiated." | 3.73 | Thyrotropin suppression by metformin. ( Filmore-Nassar, A; Glass, AR; Vigersky, RA, 2006) |
| "Metformin therapy was a nonsignificant variable in this model." | 1.39 | Relationship between serum thyrotropin concentrations and metformin therapy in euthyroid patients with type 2 diabetes. ( Díez, JJ; Iglesias, P, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ittermann, T | 1 |
| Markus, MR | 1 |
| Schipf, S | 1 |
| Derwahl, M | 1 |
| Meisinger, C | 1 |
| Völzke, H | 1 |
| Díez, JJ | 1 |
| Iglesias, P | 1 |
| Vigersky, RA | 1 |
| Filmore-Nassar, A | 1 |
| Glass, AR | 1 |
3 other studies available for metformin and Goiter
| Article | Year |
|---|---|
Metformin inhibits goitrogenous effects of type 2 diabetes.
Topics: Adult; Aged; Biomarkers; Cross-Sectional Studies; Diabetes Complications; Diabetes Mellitus, Type 2; | 2013 |
Relationship between serum thyrotropin concentrations and metformin therapy in euthyroid patients with type 2 diabetes.
Topics: Aged; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Goiter; Huma | 2013 |
Thyrotropin suppression by metformin.
Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Interactions; Female; Goiter; Graves D | 2006 |