metformin has been researched along with Glaucoma in 4 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glaucoma is the leading cause of irreversible blindness globally." | 6.72 | Metformin and Glaucoma-Review of Anti-Fibrotic Processes and Bioenergetics. ( Hurley, DJ; Irnaten, M; O'Brien, C, 2021) |
| "Our results suggest that metformin may have a protective effect on ocular complications, especially glaucoma, in patients with T2D." | 3.85 | Metformin use associated with protective effects for ocular complications in patients with type 2 diabetes - observational study. ( Burnazović-Ristić, L; Gušić, E; Kulo, A; Kusturica, J; Maleškić, S; Rakanović-Todić, M; Šečić, D, 2017) |
| "Glaucoma is the leading cause of irreversible blindness globally." | 2.72 | Metformin and Glaucoma-Review of Anti-Fibrotic Processes and Bioenergetics. ( Hurley, DJ; Irnaten, M; O'Brien, C, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, L | 1 |
| Zhang, X | 1 |
| Zhao, Y | 1 |
| Gang, X | 1 |
| Zhou, T | 1 |
| Han, J | 1 |
| Cao, Y | 1 |
| Qi, B | 1 |
| Song, S | 1 |
| Wang, X | 1 |
| Liang, Y | 1 |
| Hurley, DJ | 1 |
| Irnaten, M | 1 |
| O'Brien, C | 1 |
| Maleškić, S | 1 |
| Kusturica, J | 1 |
| Gušić, E | 1 |
| Rakanović-Todić, M | 1 |
| Šečić, D | 1 |
| Burnazović-Ristić, L | 1 |
| Kulo, A | 1 |
| Rowan, S | 1 |
| Taylor, A | 1 |
2 reviews available for metformin and Glaucoma
| Article | Year |
|---|---|
Metformin and Glaucoma-Review of Anti-Fibrotic Processes and Bioenergetics.
Topics: Animals; Fibrosis; Glaucoma; Humans; Metformin; Signal Transduction | 2021 |
The Role of Microbiota in Retinal Disease.
Topics: Animals; Conjunctiva; Cornea; Diabetic Retinopathy; Disease Models, Animal; Gastrointestinal Microbi | 2018 |
2 other studies available for metformin and Glaucoma
| Article | Year |
|---|---|
Metformin protects trabecular meshwork against oxidative injury via activating integrin/ROCK signals.
Topics: Animals; Cells, Cultured; Glaucoma; Glaucoma, Open-Angle; Humans; Integrins; Metformin; Mice; Ocular | 2023 |
Metformin use associated with protective effects for ocular complications in patients with type 2 diabetes - observational study.
Topics: Aged; Aged, 80 and over; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Eye; Female | 2017 |