metformin has been researched along with Chronic Primary Open Angle Glaucoma in 6 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether the caloric restriction mimetic drug metformin hydrochloride is associated with reduced risk of open-angle glaucoma (OAG) in persons with diabetes mellitus." | 7.81 | Association of Geroprotective Effects of Metformin and Risk of Open-Angle Glaucoma in Persons With Diabetes Mellitus. ( Childers, D; Lin, HC; Nan, B; Newman-Casey, PA; Richards, JE; Stein, JD; Thompson, DA, 2015) |
| "Recent studies suggest that the diabetes drug metformin has a protective effect on open-angle glaucoma (OAG) and age-related macular degeneration (AMD)." | 4.12 | Association of Diabetes Medication With Open-Angle Glaucoma, Age-Related Macular Degeneration, and Cataract in the Rotterdam Study. ( Ahmadizar, F; Kavousi, M; Klaver, CCW; Ramdas, WD; Stricker, BH; Thee, EF; van Duijn, CM; Vergroesen, JE, 2022) |
| " The association between the subjects who were on metformin for treatment of diabetes mellitus and development of incident POAG was assessed." | 4.02 | Association of metformin use among diabetics and the incidence of primary open-angle glaucoma - The Chennai Eye Disease Incidence Study. ( Asokan, R; George, R; Vijaya, L, 2021) |
| "To determine whether the caloric restriction mimetic drug metformin hydrochloride is associated with reduced risk of open-angle glaucoma (OAG) in persons with diabetes mellitus." | 3.81 | Association of Geroprotective Effects of Metformin and Risk of Open-Angle Glaucoma in Persons With Diabetes Mellitus. ( Childers, D; Lin, HC; Nan, B; Newman-Casey, PA; Richards, JE; Stein, JD; Thompson, DA, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 5 (83.33) | 2.80 |
| Authors | Studies |
|---|---|
| George, R | 1 |
| Asokan, R | 1 |
| Vijaya, L | 1 |
| Kumar, N | 1 |
| Amin, SV | 1 |
| Khanna, S | 1 |
| Parvar, SP | 1 |
| Shaw, LT | 1 |
| Dao, D | 1 |
| Hariprasad, SM | 1 |
| Skondra, D | 1 |
| Vergroesen, JE | 1 |
| Thee, EF | 1 |
| Ahmadizar, F | 1 |
| van Duijn, CM | 1 |
| Stricker, BH | 1 |
| Kavousi, M | 1 |
| Klaver, CCW | 1 |
| Ramdas, WD | 1 |
| Xu, L | 1 |
| Zhang, X | 1 |
| Zhao, Y | 1 |
| Gang, X | 1 |
| Zhou, T | 1 |
| Han, J | 1 |
| Cao, Y | 1 |
| Qi, B | 1 |
| Song, S | 1 |
| Wang, X | 1 |
| Liang, Y | 1 |
| Lin, HC | 1 |
| Stein, JD | 1 |
| Nan, B | 1 |
| Childers, D | 1 |
| Newman-Casey, PA | 1 |
| Thompson, DA | 1 |
| Richards, JE | 1 |
1 review available for metformin and Chronic Primary Open Angle Glaucoma
| Article | Year |
|---|---|
Metformin and retinal diseases in preclinical and clinical studies: Insights and review of literature.
Topics: Animals; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Glaucoma, Open-Angle; Macular Degeneration | 2022 |
5 other studies available for metformin and Chronic Primary Open Angle Glaucoma
| Article | Year |
|---|---|
Association of metformin use among diabetics and the incidence of primary open-angle glaucoma - The Chennai Eye Disease Incidence Study.
Topics: Cohort Studies; Diabetes Mellitus; Glaucoma, Open-Angle; Humans; Incidence; India; Intraocular Press | 2021 |
Commentary - Association of metformin use among diabetics and the incidence of primary open-angle glaucoma - The Chennai Eye Disease Incidence Study.
Topics: Cohort Studies; Diabetes Mellitus; Glaucoma, Open-Angle; Humans; Incidence; India; Intraocular Press | 2021 |
Association of Diabetes Medication With Open-Angle Glaucoma, Age-Related Macular Degeneration, and Cataract in the Rotterdam Study.
Topics: Aged; Cataract; Cohort Studies; Diabetes Mellitus, Type 2; Female; Glaucoma, Open-Angle; Humans; Ins | 2022 |
Metformin protects trabecular meshwork against oxidative injury via activating integrin/ROCK signals.
Topics: Animals; Cells, Cultured; Glaucoma; Glaucoma, Open-Angle; Humans; Integrins; Metformin; Mice; Ocular | 2023 |
Association of Geroprotective Effects of Metformin and Risk of Open-Angle Glaucoma in Persons With Diabetes Mellitus.
Topics: Adult; Aged; Aged, 80 and over; Biomimetics; Blood Glucose; Caloric Restriction; Diabetes Mellitus; | 2015 |