metformin has been researched along with Geographic Atrophy in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Geographic Atrophy: A form of MACULAR DEGENERATION also known as dry macular degeneration marked by occurrence of a well-defined progressive lesion or atrophy in the central part of the RETINA called the MACULA LUTEA. It is distinguishable from WET MACULAR DEGENERATION in that the latter involves neovascular exudates.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate if metformin use is associated with decreased odds of developing new non-neovascular ("dry") age-related macular degeneration (AMD)." | 8.31 | Association of Metformin and Other Diabetes Medication Use and the Development of New-Onset Dry Age-Related Macular Degeneration: A Case-Control Study. ( Gonnah, R; Hariprasad, S; Hyman, MJ; Kaufmann, GT; Skondra, D, 2023) |
| "To investigate if metformin use is associated with decreased odds of developing new non-neovascular ("dry") age-related macular degeneration (AMD)." | 4.31 | Association of Metformin and Other Diabetes Medication Use and the Development of New-Onset Dry Age-Related Macular Degeneration: A Case-Control Study. ( Gonnah, R; Hariprasad, S; Hyman, MJ; Kaufmann, GT; Skondra, D, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaufmann, GT | 1 |
| Hyman, MJ | 1 |
| Gonnah, R | 1 |
| Hariprasad, S | 1 |
| Skondra, D | 1 |
| Brown, EE | 1 |
| Lewin, AS | 1 |
| Ash, JD | 1 |
1 review available for metformin and Geographic Atrophy
| Article | Year |
|---|---|
Mitochondria: Potential Targets for Protection in Age-Related Macular Degeneration.
Topics: Adenylate Kinase; Animals; Disease Models, Animal; DNA, Mitochondrial; Drug Evaluation, Preclinical; | 2018 |
1 other study available for metformin and Geographic Atrophy
| Article | Year |
|---|---|
Association of Metformin and Other Diabetes Medication Use and the Development of New-Onset Dry Age-Related Macular Degeneration: A Case-Control Study.
Topics: Case-Control Studies; Diabetes Mellitus; Diabetic Retinopathy; Geographic Atrophy; Humans; Macular D | 2023 |