Page last updated: 2024-10-30

metformin and Gastroesophageal Reflux

metformin has been researched along with Gastroesophageal Reflux in 5 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Gastroesophageal Reflux: Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.

Research Excerpts

ExcerptRelevanceReference
"Chemoprevention in Barrett's esophagus is currently applied only in research settings."2.52Chemoprevention in Barrett's Esophagus: Current Status. ( Baruah, A; Buttar, NS; Kossak, SK; Zeb, MH, 2015)
"Gastrointestinal discomfort is the most common adverse event of metformin treatment for type 2 diabetes, especially in elderly patients."1.56Comparison of gastrointestinal adverse events with different doses of metformin in the treatment of elderly people with type 2 diabetes. ( Cuiping, J; Haidong, W; Jiao, S; Jieyuzhen, Q; Qin, G; Wen, T; Xiaoming, T; Yuxin, H; Zhijun, B, 2020)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Yuxin, H1
Cuiping, J1
Wen, T1
Jieyuzhen, Q1
Xiaoming, T1
Qin, G1
Haidong, W1
Jiao, S1
Zhijun, B1
Inci, F1
Atmaca, M1
Ozturk, M1
Yildiz, S1
Koceroglu, R1
Sekeroglu, R1
Ipekci, SH1
Kebapcilar, L1
Zeb, MH1
Baruah, A1
Kossak, SK1
Buttar, NS1
Taylor, SA1
Himes, R1
Hastings, E1
Garland, B1
Boehm, KM1
Gunaga, S1

Reviews

2 reviews available for metformin and Gastroesophageal Reflux

ArticleYear
Chemoprevention in Barrett's Esophagus: Current Status.
    Gastroenterology clinics of North America, 2015, Volume: 44, Issue:2

    Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Barrett Esophagus; Bile Acids and Salts; Cy

2015
Gastrointestinal Conditions in the Obese Patient.
    Adolescent medicine: state of the art reviews, 2016,Spring, Volume: 27, Issue:1

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Constipation; Contraceptiv

2016

Other Studies

3 other studies available for metformin and Gastroesophageal Reflux

ArticleYear
Comparison of gastrointestinal adverse events with different doses of metformin in the treatment of elderly people with type 2 diabetes.
    Journal of clinical pharmacy and therapeutics, 2020, Volume: 45, Issue:3

    Topics: Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; China; Diabetes Mellitus, Type 2;

2020
Pantoprazole may improve beta cell function and diabetes mellitus.
    Journal of endocrinological investigation, 2014, Volume: 37, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Ulcer Agents; Cohort Studies;

2014
Cimetidine-induced lactic acidosis and acute pancreatitis.
    Southern medical journal, 2010, Volume: 103, Issue:8

    Topics: Acidosis, Lactic; Acute Disease; Cimetidine; Diabetes Mellitus, Type 2; Drug Interactions; Female; G

2010