metformin has been researched along with Gallbladder Neoplasms in 3 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Gallbladder Neoplasms: Tumors or cancer of the gallbladder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gallbladder cancer is the most common biliary tract cancer with poor prognosis and wide variation in incidence rates worldwide, being very high in some countries in Latin America and Asia." | 1.56 | Anti-diabetic drug metformin inhibits cell proliferation and tumor growth in gallbladder cancer via G0/G1 cell cycle arrest. ( Chiyo, T; Fujihara, S; Iwama, H; Kamada, H; Kato, K; Kobara, H; Kobayashi, K; Masaki, T; Morishita, A; Okano, K; Suzuki, Y; Tsutsui, K; Yamana, H; Yamashita, T, 2020) |
| "Metformin has been identified as an antitumor drug in various tumor types." | 1.48 | Metformin suppresses hypoxia‑induced migration via the HIF‑1α/VEGF pathway in gallbladder cancer in vitro and in vivo. ( Chen, K; Li, R; Qi, L; Tang, H; Ye, J; Zhai, W; Zhou, C, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Yamashita, T | 1 |
| Kato, K | 1 |
| Fujihara, S | 1 |
| Iwama, H | 1 |
| Morishita, A | 1 |
| Yamana, H | 1 |
| Kobayashi, K | 1 |
| Kamada, H | 1 |
| Chiyo, T | 1 |
| Kobara, H | 1 |
| Tsutsui, K | 1 |
| Okano, K | 1 |
| Suzuki, Y | 1 |
| Masaki, T | 1 |
| Liu, Y | 2 |
| Wang, Z | 1 |
| Li, M | 1 |
| Ye, Y | 1 |
| Xu, Y | 1 |
| Zhang, Y | 2 |
| Yuan, R | 1 |
| Jin, Y | 1 |
| Hao, Y | 1 |
| Jiang, L | 1 |
| Hu, Y | 1 |
| Chen, S | 1 |
| Liu, F | 1 |
| Wu, W | 1 |
| Ye, J | 1 |
| Chen, K | 1 |
| Qi, L | 1 |
| Li, R | 1 |
| Tang, H | 1 |
| Zhou, C | 1 |
| Zhai, W | 1 |
3 other studies available for metformin and Gallbladder Neoplasms
| Article | Year |
|---|---|
Anti-diabetic drug metformin inhibits cell proliferation and tumor growth in gallbladder cancer via G0/G1 cell cycle arrest.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; G1 Phase Cell Cycle Checkpoints; Gallbladder Neoplasm | 2020 |
Chloride intracellular channel 1 regulates the antineoplastic effects of metformin in gallbladder cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloride Chan | 2017 |
Metformin suppresses hypoxia‑induced migration via the HIF‑1α/VEGF pathway in gallbladder cancer in vitro and in vivo.
Topics: Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gallbladder Neoplasms; Gene Expre | 2018 |